Novel role for non-muscle myosin light chain kinase (MLCK) in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation, and reactive oxygen species generation in lung endothelium.
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NADPH oxidases in lung health and diseaseReactive oxygen species in inflammation and tissue injuryRole of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.Heat Shock Protein 70 Prevents Hyperoxia-Induced Disruption of Lung Endothelial Barrier via Caspase-Dependent and AIF-Dependent PathwaysInhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia.MicroRNA regulation of nonmuscle myosin light chain kinase expression in human lung endothelium.Regulation of 130-kDa smooth muscle myosin light chain kinase expression by an intronic CArG element.Lysophosphatidic acid receptor-2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice.The fate of the primary cilium during myofibroblast transitionIntermittent hypoxia-induced endothelial barrier dysfunction requires ROS-dependent MAP kinase activation.Redox regulation of vascular remodeling.Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling.Cytotoxicity and metabolic stress induced by acetaldehyde in human intestinal LS174T goblet-like cells.Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets.Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.Phospholipase D signaling mediates reactive oxygen species-induced lung endothelial barrier dysfunction.Non-muscular myosin light chain kinase triggers intermittent hypoxia-induced interleukin-6 release, endothelial dysfunction and permeability.Integration of TRPC6 and NADPH oxidase activation in lysophosphatidylcholine-induced TRPC5 externalization.Inhibition of myosin light chain kinase reduces NADPH oxidase-mediated oxidative injury in rat brain following cerebral ischemia/reperfusion.Human and mouse microarrays-guided expression analysis of membrane protein trafficking-related genes in MDCK cells, a canine epithelial model for apical and basolateral differential protein targeting.
P2860
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P2860
Novel role for non-muscle myosin light chain kinase (MLCK) in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation, and reactive oxygen species generation in lung endothelium.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Novel role for non-muscle myos ...... eneration in lung endothelium.
@ast
Novel role for non-muscle myos ...... eneration in lung endothelium.
@en
type
label
Novel role for non-muscle myos ...... eneration in lung endothelium.
@ast
Novel role for non-muscle myos ...... eneration in lung endothelium.
@en
prefLabel
Novel role for non-muscle myos ...... eneration in lung endothelium.
@ast
Novel role for non-muscle myos ...... eneration in lung endothelium.
@en
P2093
P2860
P356
P1476
Novel role for non-muscle myos ...... eneration in lung endothelium.
@en
P2093
Donghong He
Irina A Gorshkova
Jaideep Moitra
Joe G N Garcia
Patrick A Singleton
Peter V Usatyuk
Sara M Camp
Satish K Kalari
Srikanth Pendyala
Steven M Dudek
P2860
P304
P356
10.1074/JBC.M111.294546
P407
P577
2012-01-04T00:00:00Z