The effects of chromatin organization on variation in mutation rates in the genome.
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New insights into the generation and role of de novo mutations in health and diseaseRegional Differences in the Accumulation of SNPs on the Male-Specific Portion of the Human Y Chromosome Replicate Autosomal Patterns: Implications for Genetic DatingIntegration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data AnalysisReconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data.Evidence of selection for an accessible nucleosomal array in humanMutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer TypesThe Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin FibroblastsEffects of DNA Methylation and Chromatin State on Rates of Molecular Evolution in InsectsAre sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors?Nucleotide diversity analysis highlights functionally important genomic regionsDevelopment of a 690 K SNP array in catfish and its application for genetic mapping and validation of the reference genome sequence.Epigenetic germline inheritance in mammals: Looking to the past to understand the future.Functional variomics and network perturbation: connecting genotype to phenotype in cancer.Parent-of-origin-specific signatures of de novo mutations.Differences between the genomes of lymphoblastoid cell lines and blood-derived samples.PREVENTING THE CHROMOSOMAL TRANSLOCATIONS THAT CAUSE CANCERPreferential Protection of Genetic Fidelity within Open Chromatin by the Mismatch Repair MachineryHow to tackle antimalarial resistance?Mutation hotspots in cis-regulatory regions in cancer.Three-dimensional genome architecture and emerging technologies: looping in disease.Priming for tolerance and cohesion at replication forks.Expanded molecular interrogation for potential actionable targets in non-squamous non-small cell lung cancer.Mechanisms and consequences of diversity-generating immune strategies.Direct Determination of the Mutation Rate in the Bumblebee Reveals Evidence for Weak Recombination-Associated Mutation and an Approximate Rate Constancy in Insects.Genome evolution is driven by gene expression-generated biophysical constraints through RNA-directed genetic variation: A hypothesis.Genomes of Multicellular Organisms Have Evolved to Attract Nucleosomes to Promoter Regions.Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.The role of non-genetic inheritance in evolutionary rescue: epigenetic buffering, heritable bet hedging and epigenetic traps.Mutation rate analysis via parent-progeny sequencing of the perennial peach. I. A low rate in woody perennials and a higher mutagenicity in hybrids.Divergent genome evolution caused by regional variation in DNA gain and loss between human and mouse.Base-Biased Evolution of Disease-Associated Mutations in the Human Genome.Distinctive types of postzygotic single-nucleotide mosaicisms in healthy individuals revealed by genome-wide profiling of multiple organs.Covariation in levels of nucleotide diversity in homologous regions of the avian genome long after completion of lineage sorting.Mutation rate analysis via parent-progeny sequencing of the perennial peach. II. No evidence for recombination-associated mutation.3C and 3C-based techniques: the powerful tools for spatial genome organization deciphering.
P2860
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P2860
The effects of chromatin organization on variation in mutation rates in the genome.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The effects of chromatin organization on variation in mutation rates in the genome.
@ast
The effects of chromatin organization on variation in mutation rates in the genome.
@en
type
label
The effects of chromatin organization on variation in mutation rates in the genome.
@ast
The effects of chromatin organization on variation in mutation rates in the genome.
@en
prefLabel
The effects of chromatin organization on variation in mutation rates in the genome.
@ast
The effects of chromatin organization on variation in mutation rates in the genome.
@en
P2860
P356
P1476
The effects of chromatin organization on variation in mutation rates in the genome.
@en
P2093
Kateryna D Makova
P2860
P2888
P304
P356
10.1038/NRG3890
P577
2015-03-03T00:00:00Z