Melanocyte antigen triggers autoimmunity in human psoriasis. - Wikidata - wikimedia - TriplyDB

Melanocyte antigen triggers autoimmunity in human psoriasis.

Melanocyte antigen triggers autoimmunity in human psoriasis.

http://www.wikidata.org/entity/Q35856465

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Recent advances in understanding psoriasis T Helper Cell Subsets in Clinical Manifestations of Psoriasis Evolution, immunity and the emergence of brain superautoantigens An autoimmune "attack" on melanocytes triggers psoriasis and cellular hyperplasia.Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a The role of IL-23 and the IL-23/TH 17 immune axis in the pathogenesis and treatment of psoriasis.The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies.New therapies for psoriasis and psoriatic arthritis.Ixekizumab for treatment of adults with moderate-to-severe plaque psoriasis and psoriatic arthritis.Skin under Tnf influence: how regulatory T cells work against macrophages in psoriasis.Understanding Human Autoimmunity and Autoinflammation Through Transcriptomics.IL-17 and IL-22 in immunity: Driving protection and pathology.Psoriasis: a mixed autoimmune and autoinflammatory disease.HLA-Cw6 homozygosity in plaque psoriasis is associated with streptococcal throat infections and pronounced improvement after tonsillectomy: A prospective case series.CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice.The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function.Lentiginous eruption in resolving psoriasis plaques during treatment with ixekizumab: a case report and review of the literature.Clinically resolved psoriatic lesions contain psoriasis-specific IL-17-producing αβ T cell clones.Psoriasis pathogenesis and the development of novel targeted immune therapies.The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.Autoantigens ADAMTSL5 and LL37 are significantly upregulated in active Psoriasis and localized with keratinocytes, dendritic cells and other leukocytes.Scanning the Immunopathogenesis of Psoriasis.Psoriasis: A STAT3-Centric View.Autoimmunity and autoimmune co-morbidities in psoriasis.TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis.The Immunogenetics of Psoriasis and Implications for Drug Repositioning.Updates on Psoriasis and Cutaneous Oncology: Proceedings from the 2017 MauiDerm Meeting.Mucocutaneous IL-17 immunity in mice and humans: host defense vs. excessive inflammation.Immune response patterns in non-communicable inflammatory skin diseases.Human Langerhans Cells with Pro-inflammatory Features Relocate within Psoriasis Lesions.Comparison of Occlusive and Open Application in a Psoriasis Plaque Test Design, Exemplarily Using Investigations of Mapracorat 0.1% Ointment versus Vehicle and Reference Drugs.ADAMTSL5 is upregulated in melanoma tissues in patients with idiopathic psoriasis vulgaris induced by nivolumab.HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis.The Genetic Basis of Psoriasis.Case of de novo psoriasis possibly triggered by nivolumab.Unmet Needs in the Field of Psoriasis: Pathogenesis and Treatment.Human Leukocyte Antigen-Class I Alleles and the Autoreactive T Cell Response in Psoriasis Pathogenesis.Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment.Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein.Serum 25-hydroxyvitamin D levels in patients with skin diseases including psoriasis, infections, and atopic dermatitis.

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P2860

Melanocyte antigen triggers autoimmunity in human psoriasis.

http://www.wikidata.org/entity/Q35856465

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Melanocyte antigen triggers autoimmunity in human psoriasis.

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Melanocyte antigen triggers autoimmunity in human psoriasis.

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Melanocyte antigen triggers autoimmunity in human psoriasis.

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Melanocyte antigen triggers autoimmunity in human psoriasis.

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Melanocyte antigen triggers autoimmunity in human psoriasis.

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Akiko Arakawa

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Claudia Kammerbauer

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Geraldine Rühl

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Jens Nickel

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Julia Stöhr

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Jörg C Prinz

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Katherina Siewert

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Kathrin Held

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Klaus Dornmair

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Michael Spannagl

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P2860

A disintegrin-like and metalloprotease domain containing thrombospondin type 1 motif-like 5 (ADAMTSL5) is a novel fibrillin-1-, fibrillin-2-, and heparin-binding member of the ADAMTS superfamily containing a netrin-like module

Deconstructing the Peptide-MHC Specificity of T Cell Recognition

Emerging roles of caspase-3 in apoptosis

Analysis of the paired TCR α- and β-chains of single human T cells

Identification of HLA-Cw6.02 and HLA-Cw7.01 allele-specific binding motifs by screening synthetic peptide libraries.

Reconstitution of paired T cell receptor alpha- and beta-chains from microdissected single cells of human inflammatory tissues.

Unbiased identification of target antigens of CD8+ T cells with combinatorial libraries coding for short peptides.

Uncovering the peptide-binding specificities of HLA-C: a general strategy to determine the specificity of any MHC class I molecule

Psoriasis--as an autoimmune disease caused by molecular mimicry.

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.

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10.1084/JEM.20151093

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