Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1 - Wikidata - wikimedia - TriplyDB

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

http://www.wikidata.org/entity/Q35856728

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The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors Pairing of homologous regions in the mouse genome is associated with transcription but not imprinting status MyoD regulates p57kip2 expression by interacting with a distant cis-element and modifying a higher order chromatin structure Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development An 11p15 imprinting centre region 2 deletion in a family with Beckwith Wiedemann syndrome provides insights into imprinting control at CDKN1C.Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome.The IG-DMR and the MEG3-DMR at human chromosome 14q32.2: hierarchical interaction and distinct functional properties as imprinting control centers.Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice The Drosophila homolog of the mammalian imprint regulator, CTCF, maintains the maternal genomic imprint in Drosophila melanogaster.Expression of a testis-specific form of Gal3st1 (CST), a gene essential for spermatogenesis, is regulated by the CTCF paralogous gene BORIS.Differential methylation persists at the mouse Rasgrf1 DMR in tissues displaying monoallelic and biallelic expression.CTCF shapes chromatin by multiple mechanisms: the impact of 20 years of CTCF research on understanding the workings of chromatin.Targeted gene suppression by inducing de novo DNA methylation in the gene promoter.Interruption of intrachromosomal looping by CCCTC binding factor decoy proteins abrogates genomic imprinting of human insulin-like growth factor II.Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.YY1's role in DNA methylation of Peg3 and Xist Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.Chromosome-wide analysis of parental allele-specific chromatin and DNA methylation.Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain Nonallelic transcriptional roles of CTCF and cohesins at imprinted loci.Chromatin insulators: a role in nuclear organization and gene expression.Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions.More than insulator: multiple roles of CTCF at the H19-Igf2 imprinted domain.Two distinct mechanisms of silencing by the KvDMR1 imprinting control region.G9a histone methyltransferase contributes to imprinting in the mouse placenta.Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.Insights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets.Genomic imprinting mechanisms in mammals.Genomic imprinting: employing and avoiding epigenetic processes.Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus.Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells.Allele-specific DNA methylation: beyond imprinting.Antisense RNAs and epigenetic regulation.Epigenetic and genetic disturbance of the imprinted 11p15 region in Beckwith-Wiedemann and Silver-Russell syndromes.Epigenetic and genetic alterations of the imprinting disorder Beckwith-Wiedemann syndrome and related disorders.A cross-talk between DNA methylation and H3 lysine 9 dimethylation at the KvDMR1 region controls the induction of Cdkn1c in muscle cells.Novel CTCF binding at a site in exon1A of BCL6 is associated with active histone marks and a transcriptionally active locus.DNA methylation dynamics of a maternally methylated DMR in the mouse Dlk1-Dio3 domain.

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Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

http://www.wikidata.org/entity/Q35856728

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

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Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

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type

label

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

@ast

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

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prefLabel

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

@ast

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

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Molecular and Cellular Biology

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Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

@en

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Elena M Pugacheva

http://www.w3.org/2001/XMLSchema#string

Galina V Fitzpatrick

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Jong-Yeon Shin

http://www.w3.org/2001/XMLSchema#string

Kavita Khatod

http://www.w3.org/2001/XMLSchema#string

Michael J Higgins

http://www.w3.org/2001/XMLSchema#string

Victor V Lobanenkov

http://www.w3.org/2001/XMLSchema#string

Youwen Yang

http://www.w3.org/2001/XMLSchema#string

Ziedulla Abdullaev

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P2860

An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes

An antisense RNA regulates the bidirectional silencing property of the Kcnq1 imprinting control region

A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome

Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

CTCF, a candidate trans-acting factor for X-inactivation choice

CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

Insulators: exploiting transcriptional and epigenetic mechanisms

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2636-2647

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scholarly article

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10.1128/MCB.02036-06

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7

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27

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2007-01-22T00:00:00Z

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6561272

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17242189

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1899897

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