Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest
about
Monitoring the Activation of the DNA Damage Response Pathway in a 3D Spheroid ModelInferring protein modulation from gene expression data using conditional mutual information.Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway fluxDependence of p53-deficient cells on the DHX9 DExH-box helicase.Characterization of Lgr5+ Progenitor Cell Transcriptomes after Neomycin Injury in the Neonatal Mouse CochleaThe Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor.CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage responseA two-step mechanism for cell fate decision by coordination of nuclear and mitochondrial p53 activities.Tethering function of the caspase cleavage fragment of Golgi protein p115 promotes apoptosis via a p53-dependent pathway.A novel function of p53: a gatekeeper of retinal detachmentTargeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cellsUBE4B targets phosphorylated p53 at serines 15 and 392 for degradationDDB2 decides cell fate following DNA damage.Nutlin-3 affects expression and function of retinoblastoma protein: role of retinoblastoma protein in cellular response to nutlin-3.Pre-clinical efficacy and synergistic potential of the MDM2-p53 antagonists, Nutlin-3 and RG7388, as single agents and in combined treatment with cisplatin in ovarian cancer.DDB2 (damaged-DNA binding protein 2) in nucleotide excision repair and DNA damage response.Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins.p53-independent effects of Mdm2.Downregulation of long non-coding RNA MEG3 in nasopharyngeal carcinoma.PAX3 in neuroblastoma: oncogenic potential, chemosensitivity and signalling pathways.p53 regulates Hsp90beta during arsenite-induced cytotoxicity in glutathione-deficient cells.Induction of Mitochondrial Dependent Apoptosis in Human Leukemia K562 Cells by Meconopsis integrifolia: A Species from Traditional Tibetan Medicine.Damaged-DNA Binding Protein-2 Drives Apoptosis Following DNA Damage.Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase.CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.The expression of COX-2, hTERT, MDM2, LATS2 and S100A2 in different types of non-small cell lung cancer (NSCLC).Long non-coding RNA Lnc-Tim3 exacerbates CD8 T cell exhaustion via binding to Tim-3 and inducing nuclear translocation of Bat3 in HCC.
P2860
Q28546906-2F3D4131-31C9-4C23-AC9D-6D3D3101D8B6Q30860211-50AB9B58-70E3-4CE6-ABBA-D9C3CFF9A435Q33655472-C9380D24-BF99-4869-B134-6608B05BC5B7Q33761586-17797A58-AC29-434C-94DB-2B63647B9C9FQ33869949-EA155274-ECFD-49A3-958F-66D8A5C7F7F0Q34030117-E9E884F9-423F-4241-94D5-D84281E98F6AQ34256564-71B6ACC3-D68E-4129-B88A-B010EB1F37A1Q34297075-915FA354-2F2F-4E4D-80F9-30E4452EF889Q34624486-3AE8F08D-0EE8-4830-A36F-4DDE0ED67F32Q36204186-089DFAFB-06F1-45C5-A742-7BEC01A00B0CQ36485161-83891628-86B4-495A-A089-A6657249A984Q36771960-07A44A74-8858-49F4-86C0-4D6D1628C741Q37249918-68D05AF4-6DF5-42D7-9CED-DC5411948048Q37446642-81CB0CB1-A0DC-4F59-9FA2-8FB458CEA9ACQ37457809-6964E528-7C36-4DCE-9A95-297420D18054Q37634889-2C198630-B047-4117-81F2-AC51E834EF3FQ38089906-8C1EE2AA-249C-4111-AA21-1FFCCC3B766BQ38247164-2E1F8615-DDE5-4C53-91AD-4D01B0380BDFQ38739424-28F19340-3AC9-4868-90C7-DC0E11E4CDD1Q39067308-A2432AD6-36F5-4EDA-B596-A892CD120133Q39919692-3FE6CF2E-8D7B-4BE5-B08B-B040C03DA806Q40777052-A61ACB93-5CB5-40FD-826D-6F6E9B0CC35BQ41834968-2DF23D3D-7A81-45BE-BD43-6D62F08879FAQ47955822-C65C1CC8-CFBF-4F0F-B20B-4F22A3010EC8Q50420474-C64AC17C-8BFE-4EB8-979A-00B4A15D13A0Q51803160-84C3A0D4-63F3-4C05-9721-902DD9BC75E3Q55007862-C071B7A1-06B0-4E67-B78A-8897CA6F5627
P2860
Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mdm2 is required for inhibitio ...... 53-dependent cell cycle arrest
@ast
Mdm2 is required for inhibitio ...... 53-dependent cell cycle arrest
@en
type
label
Mdm2 is required for inhibitio ...... 53-dependent cell cycle arrest
@ast
Mdm2 is required for inhibitio ...... 53-dependent cell cycle arrest
@en
prefLabel
Mdm2 is required for inhibitio ...... 53-dependent cell cycle arrest
@ast
Mdm2 is required for inhibitio ...... 53-dependent cell cycle arrest
@en
P2860
P356
P1476
Mdm2 is required for inhibitio ...... 53-dependent cell cycle arrest
@en
P2093
James J Manfredi
P2860
P304
P356
10.1128/MCB.01967-06
P407
P577
2007-03-19T00:00:00Z