The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke. - Wikidata - wikimedia - TriplyDB

The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

http://www.wikidata.org/entity/Q35857080

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Voltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domains Proton channel models filling the gap between experimental data and the structural rationale Precise Characterization of the Penumbra Revealed by MRI: A Modified Photothrombotic Stroke Model Study Philosophy of voltage-gated proton channels Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family The Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma.Effects of oxygen-glucose deprivation on microglial mobility and viability in developing mouse hippocampal tissues.Hydrophobic plug functions as a gate in voltage-gated proton channels.Proton channels and renal hypertensive injury: a key piece of the Dahl salt-sensitive rat puzzle?New insights on NOX enzymes in the central nervous system.In pursuit of an inhibitory drug for the proton channel Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives.Detergent screening of the human voltage-gated proton channel using fluorescence-detection size-exclusion chromatography.Evidence for functional diversity between the voltage-gated proton channel Hv1 and its closest related protein HVRP1.Hv1 proton channel opening is preceded by a voltage-independent transition.Neuronal hyperactivity recruits microglial processes via neuronal NMDA receptors and microglial P2Y12 receptors after status epilepticus.Selectivity Mechanism of the Voltage-gated Proton Channel, HV1 NADPH oxidase-2: linking glucose, acidosis, and excitotoxicity in stroke.Augmentation of M-type (KCNQ) potassium channels as a novel strategy to reduce stroke-induced brain injury.Modulation of microglial process convergence toward neuronal dendrites by extracellular calcium A specialized molecular motion opens the Hv1 voltage-gated proton channel.Promising targets of cell death signaling of NR2B receptor subunit in stroke pathogenesis.Voltage-Gated Proton Channels as Novel Drug Targets: From NADPH Oxidase Regulation to Sperm Biology A new method for evaluating regional cerebral blood flow changes: Laser speckle contrast imaging in a C57BL/6J mouse model of photothrombotic ischemia.Interrogation of the intersubunit interface of the open Hv1 proton channel with a probe of allosteric coupling.Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signaling.Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production.Tryptophan 207 is crucial to the unique properties of the human voltage-gated proton channel, hHV1.Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage.Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts Subunit interactions during cooperative opening of voltage-gated proton channels Construction and validation of a homology model of the human voltage-gated proton channel hHV1 Ion channels in innate and adaptive immunity Microglia: key elements in neural development, plasticity, and pathology Microglial P2Y12 receptors regulate microglial activation and surveillance during neuropathic pain.Perceptual judgements and chronic imaging of altered odour maps indicate comprehensive stimulus template matching in olfaction.P2X7 receptor activation regulates microglial cell death during oxygen-glucose deprivation.Microglial ion channels as potential targets for neuroprotection in Parkinson's disease.Molecular mechanism of Zn2+ inhibition of a voltage-gated proton channel Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1.

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P2860

The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

http://www.wikidata.org/entity/Q35857080

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The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

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The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

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The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

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The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

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The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

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The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

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Nature Neuroscience

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The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke.

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Amanda Baker

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David E Clapham

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Edward P Feener

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Frederic H Fahey

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Gongxiong Wu

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Hongbo R Luo

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Long-Jun Wu

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M Reza Akhavan Sharif

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Yonghui Jia

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P2860

A voltage-gated proton-selective channel lacking the pore domain

A voltage sensor-domain protein is a voltage-gated proton channel

Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

Voltage-gated proton channels: what's next?

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

Reversible middle cerebral artery occlusion without craniectomy in rats

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

ATP mediates rapid microglial response to local brain injury in vivo

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3314139

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