Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1.
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Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individualsEvolution of proviral gp120 over the first year of HIV-1 subtype C infectionViral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization BreadthAutologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeysAppreciating HIV type 1 diversity: subtype differences in Env.Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways.Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection.Envelope vaccination shapes viral envelope evolution following simian immunodeficiency virus infection in rhesus monkeys.Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.Temporal analysis of HIV envelope sequence evolution and antibody escape in a subtype A-infected individual with a broad neutralizing antibody responseGenetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.Functional properties of the HIV-1 subtype C envelope glycoprotein associated with mother-to-child transmissionEvolutionary and structural features of the C2, V3 and C3 envelope regions underlying the differences in HIV-1 and HIV-2 biology and infection.Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.A comparative study of HIV-1 clade C env evolution in a Zambian infant with an infected rhesus macaque during disease progression.Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection.Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infectionsMolecular evolution of HIV-1 CRF01_AE Env in Thai patientsVariations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade C env clones obtained at different time points from antiretroviral naïve Indian patients with recent infection.HIV-1 subtype C envelope characteristics associated with divergent rates of chronic disease progressionSpecificity of the autologous neutralizing antibody responseIdentification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120.Unique C2V3 sequence in HIV-1 envelope obtained from broadly neutralizing plasma of a slow progressing patient conferred enhanced virus neutralization.A single amino acid substitution in the C4 region in gp120 confers enhanced neutralization of HIV-1 by modulating CD4 binding sites and V3 loop.The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter.A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein.HIV-1 envelope glycoprotein variable loops are indispensable for envelope structural integrity and virus entry.Genetic imprint of vaccination on simian/human immunodeficiency virus type 1 transmitted viral genomes in rhesus macaquesAntibody-dependent cell-mediated viral inhibition emerges after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys coincident with gp140-binding antibodies and is effective against neutralization-resistant viruses.Phylogenetic characterisation of naturally occurring feline immunodeficiency virus in the United Kingdom.Detection of HIV-1 neutralizing antibodies in a human CD4⁺/CXCR4⁺/CCR5⁺ T-lymphoblastoid cell assay system.Molecular characterization of HIV-1 subtype C gp-120 regions potentially involved in virus adaptive mechanisms.epitopes immediately below the base of the V3 loop of gp120 as targets for the initial autologous neutralizing antibody response in two HIV-1 subtype B-infected individuals.Feline immunodeficiency virus (FIV) neutralization: a reviewIdentification of CD4-Binding Site Dependent Plasma Neutralizing Antibodies in an HIV-1 Infected Indian Individual.Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes.Clade-specific differences between human immunodeficiency virus type 1 clades B and C: diversity and correlations in C3-V4 regions of gp120.Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.Envelope variation as a primary determinant of lentiviral vaccine efficacy.Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses.
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P2860
Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Unique mutational patterns in ...... immunodeficiency virus type 1.
@ast
Unique mutational patterns in ...... immunodeficiency virus type 1.
@en
type
label
Unique mutational patterns in ...... immunodeficiency virus type 1.
@ast
Unique mutational patterns in ...... immunodeficiency virus type 1.
@en
prefLabel
Unique mutational patterns in ...... immunodeficiency virus type 1.
@ast
Unique mutational patterns in ...... immunodeficiency virus type 1.
@en
P2093
P2860
P50
P356
P1433
P1476
Unique mutational patterns in ...... immunodeficiency virus type 1.
@en
P2093
Cynthia A Derdeyn
Eric Hunter
Jeffrey N Sfakianos
Jerry L Blackwell
Jesse Taylor
John L Mokili
Joseph Mulenga
Julie M Decker
Susan Allen
P2860
P304
P356
10.1128/JVI.00257-07
P407
P577
2007-03-14T00:00:00Z