Unique pathology in simian immunodeficiency virus-infected rapid progressor macaques is consistent with a pathogenesis distinct from that of classical AIDS.
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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cellsTreatment with IL-7 prevents the decline of circulating CD4+ T cells during the acute phase of SIV infection in rhesus macaquesLife and death as a T lymphocyte: from immune protection to HIV pathogenesisAssociation of progressive CD4(+) T cell decline in SIV infection with the induction of autoreactive antibodiesPathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts.Generation of the pathogenic R5-tropic simian/human immunodeficiency virus SHIVAD8 by serial passaging in rhesus macaquesEarly lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection.Is an HIV vaccine possible?Adoption of an "open" envelope conformation facilitating CD4 binding and structural remodeling precedes coreceptor switch in R5 SHIV-infected macaques.Impact of short-term HAART initiated during the chronic stage or shortly post-exposure on SIV infection of male genital organs.Laser capture microdissection assessment of virus compartmentalization in the central nervous systems of macaques infected with neurovirulent simian immunodeficiency virusB cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllersExtended safety and efficacy studies of a live attenuated double leucine and pantothenate auxotroph of Mycobacterium tuberculosis as a vaccine candidate.Recombination-mediated changes in coreceptor usage confer an augmented pathogenic phenotype in a nonhuman primate model of HIV-1-induced AIDS.Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaquesNo acquisition: a new ambition for HIV vaccine development?Detection of Simian Immunodeficiency Virus in Semen, Urethra, and Male Reproductive Organs during Efficient Highly Active Antiretroviral TherapyHistocultures (tissue explants) in human retrovirologyA rapid progressor-specific variant clone of simian immunodeficiency virus replicates efficiently in vivo only in the absence of immune responses.Vpx is critical for SIVmne infection of pigtail macaques.Reduced Simian Immunodeficiency Virus Replication in Macrophages of Sooty Mangabeys Is Associated with Increased Expression of Host Restriction Factors.Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies.Use of human tissue explants to study human infectious agents.Identification of interdependent variables that influence coreceptor switch in R5 SHIV(SF162P3N)-infected macaques.Virus-encoded TLR ligands reveal divergent functional responses of mononuclear phagocytes in pathogenic simian immunodeficiency virus infection.Increased loss of CCR5+ CD45RA- CD4+ T cells in CD8+ lymphocyte-depleted Simian immunodeficiency virus-infected rhesus monkeysMacaques vaccinated with live-attenuated SIV control replication of heterologous virus.Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaquesGenetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic simian-human immunodeficiency virus infection.Partial protection of Simian immunodeficiency virus (SIV)-infected rhesus monkeys against superinfection with a heterologous SIV isolate.Retinoblastoma protein induction by HIV viremia or CCR5 in monocytes exposed to HIV-1 mediates protection from activation-induced apoptosis: ex vivo and in vitro study.DNA-MVA vaccine protection after X4 SHIV challenge in macaques correlates with day-of-challenge antiviral CD4+ cell-mediated immunity levels and postchallenge preservation of CD4+ T cell memory.Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus Infections.Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challengeIntrathecal humoral responses are inversely associated with the frequency of simian immunodeficiency virus macrophage-tropic variants in the central nervous systemInfection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections.Optimization of PCR for quantification of simian immunodeficiency virus genomic RNA in plasma of rhesus macaques (Macaca mulatta) using armored RNACoreceptor use in nonhuman primate models of HIV infection.Stepping toward a macaque model of HIV-1 induced AIDS.Critical Role for Monocytes/Macrophages in Rapid Progression to AIDS in Pediatric Simian Immunodeficiency Virus-Infected Rhesus Macaques.
P2860
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P2860
Unique pathology in simian immunodeficiency virus-infected rapid progressor macaques is consistent with a pathogenesis distinct from that of classical AIDS.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Unique pathology in simian imm ...... t from that of classical AIDS.
@ast
Unique pathology in simian imm ...... t from that of classical AIDS.
@en
type
label
Unique pathology in simian imm ...... t from that of classical AIDS.
@ast
Unique pathology in simian imm ...... t from that of classical AIDS.
@en
prefLabel
Unique pathology in simian imm ...... t from that of classical AIDS.
@ast
Unique pathology in simian imm ...... t from that of classical AIDS.
@en
P2093
P2860
P356
P1433
P1476
Unique pathology in simian imm ...... t from that of classical AIDS.
@en
P2093
Charles R Brown
Ilnour Ourmanov
Juraj Kabat
Malcolm A Martin
Meggan Czapiga
Vanessa M Hirsch
Yoshiaki Nishimura
P2860
P304
P356
10.1128/JVI.00202-07
P407
P577
2007-03-21T00:00:00Z