Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis
about
The M. tuberculosis HAD phosphatase (Rv3042c) interacts with host proteins and is inhibited by ClofazimineTuberculosis therapy for 2016 and beyond.A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosisAntiinfectives targeting enzymes and the proton motive force.Clofazimine Biocrystal Accumulation in Macrophages Upregulates Interleukin 1 Receptor Antagonist Production To Induce a Systemic Anti-Inflammatory StateSynthetic investigational new drugs for the treatment of tuberculosis.Adverse effects of oral second-line antituberculosis drugs in children.Mechanisms of action and therapeutic efficacies of the lipophilic antimycobacterial agents clofazimine and bedaquiline.Targeting Phenotypically Tolerant Mycobacterium tuberculosis.Clofazimine has delayed antimicrobial activity against Mycobacterium tuberculosis both in vitro and in vivo.Targeting Mycobacterium tuberculosis Sensitivity to Thiol Stress at Acidic pH Kills the Bacterium and Potentiates Antibiotics.Combinations of Respiratory Chain Inhibitors Have Enhanced Bactericidal Activity against Mycobacterium tuberculosis.Challenges of using new and repurposed drugs for the treatment of multidrug-resistant tuberculosis in children.New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development.Hit Generation in TB Drug Discovery: From Genome to Granuloma.Multifaceted remodeling by vitamin C boosts sensitivity of Mycobacterium tuberculosis subpopulations to combination treatment by anti-tubercular drugs.Macrophage-Mediated Clofazimine Sequestration Is Accompanied by a Shift in Host Energy Metabolism.Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care.Impact of Clofazimine Dosing on Treatment-Shortening of the First-Line Regimen in a Mouse Model of Tuberculosis.
P2860
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P2860
Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Mode of Action of Clofazimine ...... nst Mycobacterium tuberculosis
@ast
Mode of Action of Clofazimine ...... nst Mycobacterium tuberculosis
@en
type
label
Mode of Action of Clofazimine ...... nst Mycobacterium tuberculosis
@ast
Mode of Action of Clofazimine ...... nst Mycobacterium tuberculosis
@en
prefLabel
Mode of Action of Clofazimine ...... nst Mycobacterium tuberculosis
@ast
Mode of Action of Clofazimine ...... nst Mycobacterium tuberculosis
@en
P2860
P356
P1476
Mode of Action of Clofazimine ...... nst Mycobacterium tuberculosis
@en
P2093
Benoit Lechartier
Stewart T Cole
P2860
P304
P356
10.1128/AAC.00395-15
P407
P577
2015-05-18T00:00:00Z