Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.
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Nitric oxide: what's new to NO?Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling.Redox Control of Vascular Function.Targeting Pulmonary Endothelial Hemoglobin α Improves Nitric Oxide Signaling and Reverses Pulmonary Artery Endothelial Dysfunction.Regulation of endothelial hemoglobin alpha expression by Kruppel-like factors.Overexpression of CYB5R3 and NQO1, two NAD+ -producing enzymes, mimics aspects of caloric restriction.
P2860
Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.
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2015 nî lūn-bûn
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name
Structure Guided Chemical Modi ...... Nitric Oxide Bioavailability.
@ast
Structure Guided Chemical Modi ...... Nitric Oxide Bioavailability.
@en
type
label
Structure Guided Chemical Modi ...... Nitric Oxide Bioavailability.
@ast
Structure Guided Chemical Modi ...... Nitric Oxide Bioavailability.
@en
prefLabel
Structure Guided Chemical Modi ...... Nitric Oxide Bioavailability.
@ast
Structure Guided Chemical Modi ...... Nitric Oxide Bioavailability.
@en
P2093
P2860
P50
P356
P1476
Structure Guided Chemical Modi ...... Nitric Oxide Bioavailability.
@en
P2093
Anh T Nguyen
Bill B Chen
Carlos J Camacho
David Koes
Dongmei Cheng
Edwin K Jackson
Fabio G Reinders
Md Mizanur Rahaman
Megan P Miller
P2860
P304
16861-16872
P356
10.1074/JBC.M114.629964
P407
P577
2015-05-22T00:00:00Z