Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention.
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Are cyclooxygenase-2 and nitric oxide involved in the dyskinesia of Parkinson's disease induced by L-DOPA?Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Vitamin D inhibits COX-2 expression and inflammatory response by targeting thioesterase superfamily member 4p27 suppresses cyclooxygenase-2 expression by inhibiting p38β and p38δ-mediated CREB phosphorylation upon arsenite exposureAnthocyanins from Vitis coignetiae Pulliat Inhibit Cancer Invasion and Epithelial-Mesenchymal Transition, but These Effects Can Be Attenuated by Tumor Necrosis Factor in Human Uterine Cervical Cancer HeLa CellsPlants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggabilityAltered prostanoid signaling contributes to increased skin tumorigenesis in Tpl2 knockout miceCyanidin-3-glucoside suppresses cytokine-induced inflammatory response in human intestinal cells: comparison with 5-aminosalicylic acidCyclooxygenase-2 is required for activated pancreatic stellate cells to respond to proinflammatory cytokinesSignal transduction pathways (MAPKs, NF-κB, and C/EBP) regulating COX-2 expression in nasal fibroblasts from asthma patients with aspirin intolerance.Antitumor and antiangiogenic activities of curcumin in cervical cancer xenografts in nude mice.p50-associated COX-2 extragenic RNA (PACER) activates COX-2 gene expression by occluding repressive NF-κB complexesp130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells.Wnt/β-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells.Celecoxib decreases growth and angiogenesis and promotes apoptosis in a tumor cell line resistant to chemotherapyCOX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation statusViscum album exerts anti-inflammatory effect by selectively inhibiting cytokine-induced expression of cyclooxygenase-2.Docosahexaenoic acid inhibits UVB-induced activation of NF-κB and expression of COX-2 and NOX-4 in HR-1 hairless mouse skin by blocking MSK1 signaling.Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells.Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis.Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kappaB and AP-1: IkappaB kinase and c-Jun-N-terminal kinase as respective potential upstream targets.Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2.An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models.The MIF homologue D-dopachrome tautomerase promotes COX-2 expression through β-catenin-dependent and -independent mechanisms.Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells.TGF-β1 downregulates COX-2 expression leading to decrease of PGE2 production in human lung cancer A549 cells, which is involved in fibrotic response to TGF-β1.Viscum album-mediated COX-2 inhibition implicates destabilization of COX-2 mRNANoninvasive imaging identifies new roles for cyclooxygenase-2 in choline and lipid metabolism of human breast cancer cellsPharmGKB summary: very important pharmacogene information for PTGS2.TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells.Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases.Apoptotic effects of two COX-2 inhibitors on breast adenocarcinoma cells through COX-2 independent pathway.Decreased expression of the NF-κB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression.Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin: extracellular signal-regulated kinase and nuclear factor-κB as potential targetsInsulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells.Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2'-O-acetyl-α-L-rhamnosyloxy)benzyl]isothiocyanate from Moringa oleifera.Comparison of anti-inflammatory activities of an anthocyanin-rich fraction from Portuguese blueberries (Vaccinium corymbosum L.) and 5-aminosalicylic acid in a TNBS-induced colitis rat modelCXC chemokine ligand 12/stromal cell-derived factor-1 regulates cell adhesion in human colon cancer cells by induction of intercellular adhesion molecule-1CpG oligodeoxynucleotides induce cyclooxygenase-2 in human B lymphocytes: implications for adjuvant activity and antibody production.The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation.
P2860
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P2860
Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Signal transduction pathways r ...... r targets for chemoprevention.
@ast
Signal transduction pathways r ...... r targets for chemoprevention.
@en
type
label
Signal transduction pathways r ...... r targets for chemoprevention.
@ast
Signal transduction pathways r ...... r targets for chemoprevention.
@en
prefLabel
Signal transduction pathways r ...... r targets for chemoprevention.
@ast
Signal transduction pathways r ...... r targets for chemoprevention.
@en
P1476
Signal transduction pathways r ...... r targets for chemoprevention.
@en
P2093
Kyung-Soo Chun
Young-Joon Surh
P304
P356
10.1016/J.BCP.2004.05.031
P407
P577
2004-09-01T00:00:00Z