CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine
about
The emerging role of CaMKII in cancerLeukemia stem cells: the root of chronic myeloid leukemiaCaMKII plays a part in the chondrogenesis of bone marrow-derived mesenchymal stem cells.On the preparation of transferrin modified artesunate nanoliposomes and their glioma-targeting treatment in-vitro and in-vivo.Ca2+/calmodulin-dependent protein kinase IIγ enhances stem-like traits and tumorigenicity of lung cancer cells.Structure-Based Target-Specific Screening Leads to Small-Molecule CaMKII Inhibitors.Homoharringtonine targets Smad3 and TGF-β pathway to inhibit the proliferation of acute myeloid leukemia cells.Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca²⁺/calmodulin-dependent protein kinase II.Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway.CAMK2γ antagonizes mTORC1 activation during hepatocarcinogenesis.CAMK2γ in intestinal epithelial cells modulates colitis-associated colorectal carcinogenesis via enhancing STAT3 activation.Phosphorylation of calcium/calmodulin-stimulated protein kinase II at T286 enhances invasion and migration of human breast cancer cells.Wogonin suppresses human alveolar adenocarcinoma cell A549 migration in inflammatory microenvironment by modulating the IL-6/STAT3 signaling pathway.Activation of CaMKIIγ potentiates T-cell acute lymphoblastic leukemia leukemogenesis via phosphorylating FOXO3a.Berbamine inhibited the growth of prostate cancer cells in vivo and in vitro via triggering intrinsic pathway of apoptosis.Demystifying traditional herbal medicine with modern approach.Competitive Kinase Enrichment Proteomics Reveals that Abemaciclib Inhibits GSK3β and Activates WNT Signaling.Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma.Aberrant activation of CaMKIIγ accelerates chronic myeloid leukemia blast crisis.Berbamine induces SMMC-7721 cell apoptosis via upregulating p53, downregulating survivin expression and activating mitochondria signaling pathway.In vitro and in vivo metabolic activation of berbamine to quinone methide intermediate.Cryptotanshinone acts synergistically with imatinib to induce apoptosis of human chronic myeloid leukemia cells.
P2860
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P2860
CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
CaMKII γ, a critical regulator ...... the natural product berbamine
@ast
CaMKII γ, a critical regulator ...... the natural product berbamine
@en
type
label
CaMKII γ, a critical regulator ...... the natural product berbamine
@ast
CaMKII γ, a critical regulator ...... the natural product berbamine
@en
prefLabel
CaMKII γ, a critical regulator ...... the natural product berbamine
@ast
CaMKII γ, a critical regulator ...... the natural product berbamine
@en
P2093
P2860
P1433
P1476
CaMKII γ, a critical regulator ...... the natural product berbamine
@en
P2093
Hongzhi Li
Jinfen Tang
Liansheng Huang
Rongzhen Xu
P2860
P304
P356
10.1182/BLOOD-2012-06-434894
P407
P577
2012-10-16T00:00:00Z