Transient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regeneration
about
Utilization of diagnostic ultrasound and intravenous lipid-encapsulated perfluorocarbons in non-invasive targeted cardiovascular therapeutics.Ultrasound-mediated targeted drug delivery: recent success and remaining challengesThe cell cycle as a brake for β-cell regeneration from embryonic stem cellsNucleic acid delivery with microbubbles and ultrasound.Successful β cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1.Stimulation of adult resident cardiac progenitor cells by durable myocardial expression of thymosin beta 4 with ultrasound-targeted microbubble delivery.A genetic mouse model for progressive ablation and regeneration of insulin producing beta-cells.Nerve growth factor delivery by ultrasound-mediated nanobubble destruction as a treatment for acute spinal cord injury in rats.Deletion of β-Arrestin2 in mice limited pancreatic beta-cell expansion under metabolic stress through activation of JNK pathway.Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.Cyclin D2 is a GATA4 cofactor in cardiogenesis.ANGPTL8 reverses established adriamycin cardiomyopathy by stimulating adult cardiac progenitor cells.α-cell role in β-cell generation and regeneration.Prospect of ultrasound-mediated gene delivery in cardiovascular applications.mTORC1 pathway mediates beta cell compensatory proliferation in 60 % partial-pancreatectomy mice.Enhanced ultrasonography using a nano/microbubble contrast agent for islet transplantation.Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis.Engineering brown fat into skeletal muscle using ultrasound-targeted microbubble destruction gene delivery in obese Zucker rats: Proof of concept design.In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats.Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1.Mangiferin induces islet regeneration in aged mice through regulating p16INK4a.Ectopic transgenic expression of NKX2.2 induces differentiation of adult pancreatic progenitors and mediates islet regeneration.
P2860
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P2860
Transient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regeneration
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
Transient overexpression of cy ...... nd mediates islet regeneration
@ast
Transient overexpression of cy ...... nd mediates islet regeneration
@en
type
label
Transient overexpression of cy ...... nd mediates islet regeneration
@ast
Transient overexpression of cy ...... nd mediates islet regeneration
@en
prefLabel
Transient overexpression of cy ...... nd mediates islet regeneration
@ast
Transient overexpression of cy ...... nd mediates islet regeneration
@en
P2093
P2860
P356
P1433
P1476
Transient overexpression of cy ...... nd mediates islet regeneration
@en
P2093
Jiaxi Chen
Masayuki Shimoda
Shinichi Matsumoto
Shuyuan Chen
P2860
P304
P356
10.4161/CC.11.4.19120
P577
2012-02-01T00:00:00Z