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G protein-coupled receptors and insulin secretion: 119 and counting

G protein-coupled receptors and insulin secretion: 119 and counting

http://www.wikidata.org/entity/Q35867521

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GPR119 agonists for the treatment of type 2 diabetes AMG 837: a novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents Acute exposure to a precursor of advanced glycation end products induces a dual effect on the rat pancreatic islet function.Seven transmembrane-spanning receptors for free fatty acids as therapeutic targets for diabetes mellitus: pharmacological, phylogenetic, and drug discovery aspects.Progress in the discovery and development of small-molecule modulators of G-protein-coupled receptor 40 (GPR40/FFA1/FFAR1): an emerging target for type 2 diabetes.GPR119 agonists as potential new oral agents for the treatment of type 2 diabetes and obesity.Novel GPR119 agonist HD0471042 attenuated type 2 diabetes mellitus.The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119.Monoacylglycerol signalling and ABHD6 in health and disease.Revisiting the Therapeutic Potential of Bothrops jararaca Venom: Screening for Novel Activities Using Connectivity Mapping.

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G protein-coupled receptors and insulin secretion: 119 and counting

http://www.wikidata.org/entity/Q35867521

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

G protein-coupled receptors and insulin secretion: 119 and counting

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G protein-coupled receptors and insulin secretion: 119 and counting

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G protein-coupled receptors and insulin secretion: 119 and counting

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G protein-coupled receptors and insulin secretion: 119 and counting

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G protein-coupled receptors and insulin secretion: 119 and counting

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G protein-coupled receptors and insulin secretion: 119 and counting

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G protein-coupled receptors and insulin secretion: 119 and counting

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S R Murthy Madiraju

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Triggering and amplifying pathways of regulation of insulin secretion by glucose.

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo.

GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.

Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives

The G-protein-coupled receptor 40 family (GPR40-GPR43) and its role in nutrient sensing

Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor

The biology of incretin hormones.

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2598-2600

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scholarly article

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10.1210/EN.2007-0336

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6

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Vincent Poitout

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