CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef.
about
Down-regulation of CTLA-4 by HIV-1 Nef proteinMultilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting stepsAn endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein.Human immunodeficiency virus type 1 Nef mediates sustained membrane expression of tumor necrosis factor and the related cytokine LIGHT on activated T cells.HIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elementsT helper cell activation and human retroviral pathogenesisSilencing of both beta-TrCP1 and HOS (beta-TrCP2) is required to suppress human immunodeficiency virus type 1 Vpu-mediated CD4 down-modulationTargeted infection of HIV-1 Env expressing cells by HIV(CD4/CXCR4) vectors reveals a potential new rationale for HIV-1 mediated down-modulation of CD4Targeted gene disruption to cure HIVEmergence of recombinant forms of HIV: dynamics and scalingTiming the emergence of resistance to anti-HIV drugs with large genetic barriersEastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir.Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cellsMultiploid inheritance of HIV-1 during cell-to-cell infection.Combinatorial signals from CD28 differentially regulate human immunodeficiency virus transcription in T cellsApplications of flow cytometry to clinical microbiology.Regulation of virus release by the macrophage-tropic human immunodeficiency virus type 1 AD8 isolate is redundant and can be controlled by either Vpu or Env.Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptorsTaking multiple infections of cells and recombination into account leads to small within-host effective-population-size estimates of HIV-1Human immunodeficiency virus type 2 produces a defect in CD3-gamma gene transcripts similar to that observed for human immunodeficiency virus type 1.Human immunodeficiency virus type 1 (HIV-1)-induced GRO-alpha production stimulates HIV-1 replication in macrophages and T lymphocytesHIV dynamics with multiple infections of target cells.Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes.HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells.HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs.Patterns of Human Immunodeficiency Virus type 1 recombination ex vivo provide evidence for coadaptation of distant sites, resulting in purifying selection for intersubtype recombinants during replication.Estimating frequencies of minority nevirapine-resistant strains in chronically HIV-1-infected individuals naive to nevirapine by using stochastic simulations and a mathematical model.Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication.Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latencyHIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2.Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation.Nef-mediated disruption of HLA-A2 transport to the cell surface in T cellsNef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.Supervised learning and prediction of physical interactions between human and HIV proteinsBlocking premature reverse transcription fails to rescue the HIV-1 nucleocapsid-mutant replication defect.Inhibition of retromer activity by herpesvirus saimiri tip leads to CD4 downregulation and efficient T cell transformation.Elimination of HIV-1-Infected Primary T Cell Reservoirs in an In Vitro Model of Latency.Productive infection of double-negative T cells with HIV in vivo.Replication-independent expression of anti-apoptosis marker genes in human peripheral blood mononuclear cells infected with the wild-type HIV-1 and reverse transcriptase variantsThe kappaB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth.
P2860
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P2860
CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
CD4 down-modulation during inf ...... tivities of vpu, env, and nef.
@ast
CD4 down-modulation during inf ...... tivities of vpu, env, and nef.
@en
type
label
CD4 down-modulation during inf ...... tivities of vpu, env, and nef.
@ast
CD4 down-modulation during inf ...... tivities of vpu, env, and nef.
@en
prefLabel
CD4 down-modulation during inf ...... tivities of vpu, env, and nef.
@ast
CD4 down-modulation during inf ...... tivities of vpu, env, and nef.
@en
P2860
P1433
P1476
CD4 down-modulation during inf ...... ctivities of vpu, env, and nef
@en
P2093
Baltimore D
P2860
P304
P407
P577
1996-09-01T00:00:00Z