Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets.
about
Recent advances in subtyping tumors of the central nervous system using molecular data.Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.Molecular Testing of Brain Tumor.Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification.Integrating precision cancer medicine into healthcare-policy, practice, and research challenges.Patterns of diagnostic marker assessment in adult diffuse glioma: a survey of the European Confederation of Neuropathological Societies (Euro-CNS).Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing.Same-day genomic and epigenomic diagnosis of brain tumors using real-time nanopore sequencing.Identification of T cell target antigens in glioblastoma stem-like cells using an integrated proteomics-based approach in patient specimens.Advances in the molecular genetics of gliomas - implications for classification and therapy.Characterization of gliomas: from morphology to molecules.Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter-hypermethylation - the NCT Neuro Master Match (N2M2) pilot study.Diagnostic implications of TERT promoter mutation status in diffuse gliomas in a routine clinical setting.A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors.Neurological update: gliomas and other primary brain tumours in adults.Evidence of H3 K27M mutations in posterior fossa ependymomas.Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas.Clinical significance of detecting CSF-derived tumor cells in breast cancer patients with leptomeningeal metastasis.DNA methylation-based classification of central nervous system tumours.Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.Recent Advancement of the Molecular Diagnosis in Pediatric Brain Tumor.Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and spaceMinION rapid sequencing: Review of potential applications in neurosurgeryGenetic and Epigenetic Features of Rapidly Progressing IDH-Mutant AstrocytomasA Critical Overview of Targeted Therapies for Glioblastoma
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P2860
Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
@zh-hk
2015年論文
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2015年論文
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2015年论文
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2015年论文
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name
Next-generation sequencing in ...... identifies actionable targets.
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Next-generation sequencing in ...... identifies actionable targets.
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Next-generation sequencing in ...... identifies actionable targets.
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Next-generation sequencing in ...... identifies actionable targets.
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Next-generation sequencing in ...... identifies actionable targets.
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Next-generation sequencing in ...... identifies actionable targets.
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P2093
P2860
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Next-generation sequencing in ...... identifies actionable targets.
@en
P2093
Andrey Korshunov
Annekathrin Kratz
Antje Wick
Christian Koelsche
Christian Mawrin
Christine Jungk
David Reuss
David T W Jones
Dominik Sturm
Florian Selt
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10.1007/S00401-015-1519-8
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P577
2015-12-15T00:00:00Z