Effects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pig - Wikidata - wikimedia - TriplyDB

Effects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pig

Effects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pig

http://www.wikidata.org/entity/Q35874736

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The effect of selective phosphodiesterase inhibitors, alone and in combination, on a murine model of allergic asthma Modulation of eotaxin formation and eosinophil migration by selective inhibitors of phosphodiesterase type 4 isoenzyme Effects of inhibition of PDE4 and TNF-alpha on local and remote injuries following ischaemia and reperfusion injury Cyclic AMP elevating agents and nitric oxide modulate angiotensin II-induced leukocyte-endothelial cell interactions in vivo Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis.The role of lipocortin-1 in the inhibitory action of dexamethasone on eosinophil trafficking in cutaneous inflammatory reactions in the mouse.A comparison of the inhibitory activity of PDE4 inhibitors on leukocyte PDE4 activity in vitro and eosinophil trafficking in vivo Impaired host defense to Klebsiella pneumoniae infection in mice treated with the PDE4 inhibitor rolipram Effects of dexamethasone and cyclosporin A on the accumulation of eosinophils in acute cutaneous inflammation in the guinea-pig Effects of agents which elevate cyclic AMP on guinea-pig eosinophil homotypic aggregation Chemokine-induced eosinophil recruitment. Evidence of a role for endogenous eotaxin in an in vivo allergy model in mouse skin.Anti-inflammatory effects of theophylline and selective phosphodiesterase inhibitors.Effects of theophylline and rolipram on leukotriene C4 (LTC4) synthesis and chemotaxis of human eosinophils from normal and atopic subjects.Rolipram inhibits leukocyte-endothelial cell interactions in vivo through P- and E-selectin downregulation Acute versus chronic administration of phosphodiesterase inhibitors on allergen-induced pulmonary cell influx in sensitized guinea-pigs.Effects of inhibitors of phosphodiesterase, on antigen-induced bronchial hyperreactivity in conscious sensitized guinea-pigs and airway leukocyte infiltration.Inhibition of eotaxin-mediated human eosinophil activation and migration by the selective cyclic nucleotide phosphodiesterase type 4 inhibitor rolipram.Phosphodiesterase 4 inhibition attenuates atrial natriuretic peptide-induced vascular hyperpermeability and loss of plasma volume.A comparison of the inhibitory activity of selective PDE4 inhibitors on eosinophil recruitment in guinea pig skin.Production of singlet oxygen by eosinophils activated in vitro by C5a and leukotriene B4.Phosphodiesterase 4 inhibition attenuates plasma volume loss and transvascular exchange in volume-expanded mice.

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P2860

Effects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pig

http://www.wikidata.org/entity/Q35874736

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1994 nî lūn-bûn

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J.1476-5381.1994.TB13073.X

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British Journal of Pharmacology

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Effects of phosphodiesterase i ...... inflammation in the guinea-pig

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A G Rossi

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M M Teixeira

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P G Hellewell

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T J Williams

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P2860

Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in primates.

Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response.

Theophylline in the management of airflow obstruction. 2. Difficult drugs to use, few clinical indications

Prospects for selective cyclic nucleotide phosphodiesterase inhibitors in the treatment of bronchial asthma.

Eosinophils and the pathophysiology of allergic rhinitis.

Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors.

Inhibition of eosinophil cyclic nucleotide PDE activity and opsonised zymosan-stimulated respiratory burst by 'type IV'-selective PDE inhibitors.

Role of CD18 in the accumulation of eosinophils and neutrophils and local oedema formation in inflammatory reactions in guinea-pig skin

The bronchial epithelium as a target for inflammatory attack in asthma.

Role of prostaglandins and nitric oxide in acute inflammatory reactions in guinea-pig skin.

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