The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation.
about
Cloning of ACP33 as a novel intracellular ligand of CD4Dynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transductionCrystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC moleculeSeparable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signalingSyk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complexThe multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsT cell antigen recognition at the cell membraneAffinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complexCrystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 bindingClassical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalphaModulation of CD4 lateral interaction with lymphocyte surface molecules induced by HIV-1 gp120Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagementAssociation between mitogen-activated protein kinase and the zeta chain of the T cell receptor (TcR) with the SH2,3 domain of p56lck. Differential regulation by TcR cross-linking.Regulated movement of CD4 in and out of the immunological synapseTemporal transcriptome changes induced by MDV in Marek's disease-resistant and -susceptible inbred chickens.CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.Redirecting human CD4+ T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR alphabeta gene transfer requires CD8alpha.CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses.NSOM/QD-based direct visualization of CD3-induced and CD28-enhanced nanospatial coclustering of TCR and coreceptor in nanodomains in T cell activation.Bacterial and viral superantigens: roles in autoimmunity?Absence of linkage between idiopathic dilated cardiomyopathy and candidate genes involved in the immune function in a large Italian pedigree.T cell immunity induced by a bivalent Salmonella-based CEACAM6 and 4-1BBL vaccines in a rat colorectal cancer model.Function and regulation of memory CD4 T cells.Rational design of T cell receptors with enhanced sensitivity for antigen.CD45 tyrosine phosphatase-activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influxFormation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells.Development of thymically derived natural regulatory T cells.TCR signal initiation machinery is pre-assembled and activated in a subset of membrane raftsThirty-six views of T-cell recognition.CD3Z genetic polymorphism in immune response to hepatitis B vaccination in two independent Chinese populationsAntigen-induced T cell death is regulated by CD4 expression.Transcriptional and post-transcriptional mechanisms of glucocorticoid antiproliferative effects.Extracellular domains of CD8α and CD8ß subunits are sufficient for HLA class I restricted helper functions of TCR-engineered CD4(+) T cells.A rational design approach for developing immunomodulators based on CD4 and CD8.Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lckThe T cell antigen receptor CD3:CD4 molecular complex is diminished on the surface of pulmonary lymphocytesThe Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T CellsBiological responses to spider silk-antibiotic fusion protein.
P2860
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P2860
The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
The T cell receptor as a multi ...... and CD45 in T cell activation.
@ast
The T cell receptor as a multi ...... and CD45 in T cell activation.
@en
type
label
The T cell receptor as a multi ...... and CD45 in T cell activation.
@ast
The T cell receptor as a multi ...... and CD45 in T cell activation.
@en
prefLabel
The T cell receptor as a multi ...... and CD45 in T cell activation.
@ast
The T cell receptor as a multi ...... and CD45 in T cell activation.
@en
P1476
The T cell receptor as a multi ...... and CD45 in T cell activation.
@en
P2093
Janeway CA Jr
P304
P356
10.1146/ANNUREV.IY.10.040192.003241
P577
1992-01-01T00:00:00Z