JAM-A protects from thrombosis by suppressing integrin αIIbβ3-dependent outside-in signaling in platelets.
about
Platelet signaling: a complex interplay between inhibitory and activatory networksVessel wall BAMBI contributes to hemostasis and thrombus stability.Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets.Platelets and their chemokines in atherosclerosis-clinical applications.Early Detection of Junctional Adhesion Molecule-1 (JAM-1) in the Circulation after Experimental and Clinical Polytrauma.Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis.Binding of CIB1 to the αIIb tail of αIIbβ3 is required for FAK recruitment and activation in plateletsDual mechanism of integrin αIIbβ3 closure in procoagulant plateletsHigh-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor.Junctional adhesion molecule-A suppresses platelet integrin αIIbβ3 signaling by recruiting Csk to the integrin-c-Src complex.Platelets: key players in vascular inflammation.Harnessing the platelet signaling network to produce an optimal hemostatic response.Integrin αIIbβ3 outside-in signaling.Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function.Adhesion Molecules: Master Controllers of the Circulatory System.Model systems for platelet receptor shedding.Receptor-interacting protein kinase 3 promotes platelet activation and thrombosis.Deletion of junctional adhesion molecule A from platelets increases early-stage neointima formation after wire injury in hyperlipidemic mice.EphB2 regulates contact-dependent and contact-independent signaling to control platelet function.Minding the gaps--and the junctions, too.The small molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis.Junctional adhesion molecule-A: functional diversity through molecular promiscuity.Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.Ask1 regulates murine platelet granule secretion, thromboxane A2 generation, and thrombus formation.Negative regulators of platelet activation and adhesion.Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection.Synthesis and antiplatelet activity of antithrombotic thiourea compounds: biological and structure-activity relationship studies.
P2860
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P2860
JAM-A protects from thrombosis by suppressing integrin αIIbβ3-dependent outside-in signaling in platelets.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
JAM-A protects from thrombosis ...... ide-in signaling in platelets.
@ast
JAM-A protects from thrombosis ...... ide-in signaling in platelets.
@en
type
label
JAM-A protects from thrombosis ...... ide-in signaling in platelets.
@ast
JAM-A protects from thrombosis ...... ide-in signaling in platelets.
@en
prefLabel
JAM-A protects from thrombosis ...... ide-in signaling in platelets.
@ast
JAM-A protects from thrombosis ...... ide-in signaling in platelets.
@en
P2093
P2860
P1433
P1476
JAM-A protects from thrombosis ...... side-in signaling in platelets
@en
P2093
Lawrence F Brass
Meghna U Naik
Ulhas P Naik
P2860
P304
P356
10.1182/BLOOD-2011-12-397398
P407
P577
2012-01-23T00:00:00Z