Coupling between Histone Conformations and DNA Geometry in Nucleosomes on a Microsecond Timescale: Atomistic Insights into Nucleosome Functions
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Distinct Roles of Histone H3 and H2A Tails in Nucleosome Stability.Nucleosome Histone Tail Conformation and Dynamics: Impacts of Lysine Acetylation and a Nearby Minor Groove Benzo[a]pyrene-Derived LesionHistoneDB 2.0: a histone database with variants--an integrated resource to explore histones and their variantsTrajectories of microsecond molecular dynamics simulations of nucleosomes and nucleosome core particles.Partially Assembled Nucleosome Structures at Atomic Detail.Conformational selection and dynamic adaptation upon linker histone binding to the nucleosomeHMGN1 and 2 remodel core and linker histone tail domains within chromatin.Implicit Solvent Model for Million-Atom Atomistic Simulations: Insights into the Organization of 30-nm Chromatin Fiber.Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres.Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations.Hydroxyl-radical footprinting combined with molecular modeling identifies unique features of DNA conformation and nucleosome positioning.Asymmetric breathing motions of nucleosomal DNA and the role of histone tails.Histone H3K4 and H3K36 Methylation Independently Recruit the NuA3 Histone Acetyltransferase in Saccharomyces cerevisiae.Modulation of nucleosomal DNA accessibility via charge-altering post-translational modifications in histone core.New tricks for old dogs: improving the accuracy of biomolecular force fields by pair-specific corrections to non-bonded interactions.Free energy profiles for unwrapping the outer superhelical turn of nucleosomal DNA.Towards quantitative analysis of gene regulation by enhancers.Structural rearrangements of the histone octamer translocate DNA.DNA sliding in nucleosomes via twist defect propagation revealed by molecular simulations.The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome.Mechanical evolution of DNA double-strand breaks in the nucleosome.Explicit ions/implicit water generalized Born model for nucleic acidsReplication-dependent histone isoforms: a new source of complexity in chromatin structure and function
P2860
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P2860
Coupling between Histone Conformations and DNA Geometry in Nucleosomes on a Microsecond Timescale: Atomistic Insights into Nucleosome Functions
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2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
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2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Coupling between Histone Confo ...... ghts into Nucleosome Functions
@ast
Coupling between Histone Confo ...... ghts into Nucleosome Functions
@en
type
label
Coupling between Histone Confo ...... ghts into Nucleosome Functions
@ast
Coupling between Histone Confo ...... ghts into Nucleosome Functions
@en
prefLabel
Coupling between Histone Confo ...... ghts into Nucleosome Functions
@ast
Coupling between Histone Confo ...... ghts into Nucleosome Functions
@en
P2093
P2860
P1476
Coupling between Histone Confo ...... ghts into Nucleosome Functions
@en
P2093
Alexey K Shaytan
Anna R Panchenko
Grigoriy A Armeev
Victor B Zhurkin
P2860
P304
P356
10.1016/J.JMB.2015.12.004
P407
P577
2015-12-14T00:00:00Z