Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes.
about
Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor proteinEvolution and horizontal transfer of dUTPase-encoding genes in viruses and their hostsMulti-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteinsLink of the unique oncogenic properties of adenovirus type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteinsReannotation of the CELO genome characterizes a set of previously unassigned open reading frames and points to novel modes of host interaction in avian adenovirusesThe human adenovirus E4-ORF1 protein subverts discs large 1 to mediate membrane recruitment and dysregulation of phosphatidylinositol 3-kinaseHerpesviruses dUTPases: A New Family of Pathogen-Associated Molecular Pattern (PAMP) Proteins with Implications for Human DiseaseGenomic and bioinformatics analysis of human adenovirus type 37: new insights into corneal tropism.Genomic and bioinformatics analysis of HAdV-4, a human adenovirus causing acute respiratory disease: implications for gene therapy and vaccine vector development.The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis.Recombinant, replication-defective adenovirus gene transfer vectors induce cell cycle dysregulation and inappropriate expression of cyclin proteins.Induction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA.Several E4 region functions influence mammary tumorigenesis by human adenovirus type 9Construction of avian adenovirus CELO recombinants in cosmids.Human herpesviruses-encoded dUTPases: a family of proteins that modulate dendritic cell function and innate immunityHijacking Dlg1 for oncogenic phosphatidylinositol 3-kinase activation in human epithelial cells is a conserved mechanism of human adenovirus E4-ORF1 proteins.Epstein-Barr virus encoded dUTPase containing exosomes modulate innate and adaptive immune responses in human dendritic cells and peripheral blood mononuclear cellsA new crucial protein interaction element that targets the adenovirus E4-ORF1 oncoprotein to membrane vesiclesMutant adenovirus type 9 E4 ORF1 genes define three protein regions required for transformation of CREF cells.A carboxy-terminal region required by the adenovirus type 9 E4 ORF1 oncoprotein for transformation mediates direct binding to cellular polypeptides.Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells.Functionally distinct monomers and trimers produced by a viral oncoprotein.Cell polarity proteins: common targets for tumorigenic human viruses.Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein.Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation.Mutational analysis of the avian adenovirus CELO, which provides a basis for gene delivery vectors.Adenovirus type 5 E4 open reading frame 4 protein induces apoptosis in transformed cells.Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo.Adenovirus E4-ORF1 Dysregulates Epidermal Growth Factor and Insulin/Insulin-Like Growth Factor Receptors To Mediate Constitutive Myc Expression.New genes from old: redeployment of dUTPase by herpesviruses.Targeting Nucleotide Biosynthesis: A Strategy for Improving the Oncolytic Potential of DNA Viruses.
P2860
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P2860
Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Human adenovirus early region ...... dUTP pyrophosphatase enzymes.
@ast
Human adenovirus early region ...... dUTP pyrophosphatase enzymes.
@en
type
label
Human adenovirus early region ...... dUTP pyrophosphatase enzymes.
@ast
Human adenovirus early region ...... dUTP pyrophosphatase enzymes.
@en
prefLabel
Human adenovirus early region ...... dUTP pyrophosphatase enzymes.
@ast
Human adenovirus early region ...... dUTP pyrophosphatase enzymes.
@en
P2093
P2860
P1433
P1476
Human adenovirus early region ...... dUTP pyrophosphatase enzymes.
@en
P2093
P2860
P304
P407
P577
1997-03-01T00:00:00Z