Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
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The role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implicationsAn analysis of enzyme kinetics data for mitochondrial DNA strand termination by nucleoside reverse transcription inhibitorsTenofovir renal toxicity targets mitochondria of renal proximal tubules.Transgenic cardiac-targeted overexpression of human thymidylate kinaseAzidothymidine enhances fluorodeoxyuridine-mediated radiosensitizationIn vitro mitochondrial toxicity of metacavir, a new nucleoside reverse transcriptase inhibitor for treatment of hepatitis B virus.Design, synthesis, and in vitro and in vivo biological studies of a 3'-deoxythymidine conjugate that potentially kills cancer cells selectivelyRole of cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) in the initiation of mitochondrial biogenesis and stress response in liver cellsOverexpression of mitochondrial antioxidant manganese superoxide dismutase (MnSOD) provides protection against AZT- or 3TC-induced endothelial dysfunction.HIV infection and antiretroviral therapy have divergent effects on mitochondria in adipose tissue.Metabolism of deoxypyrimidines and deoxypyrimidine antiviral analogs in isolated brain mitochondriaGenerating Rho-0 Cells Using Mesenchymal Stem Cell Lines.Impact of nucleoside reverse transcriptase inhibitors on mitochondria in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapy.Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy.Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cellsCytokine and sex hormone effects on zidovudine- and lamivudine-triphosphate concentrations in vitro.Mitochondrial RNA and DNA alterations in HIV lipoatrophy are linked to antiretroviral therapy and not to HIV infection.Effects of zidovudine and stavudine on mitochondrial DNA of differentiating 3T3-F442a cells are not associated with imbalanced deoxynucleotide pools.Long-term exposure to AZT, but not d4T, increases endothelial cell oxidative stress and mitochondrial dysfunction.Nucleoside reverse transcriptase inhibitors induce a mitophagy-associated endothelial cytotoxicity that is reversed by coenzyme Q10 cotreatment.Synthesis and Biological Evaluation of 5'-O-Dicarboxylic Fatty Acyl Monoester Derivatives of Anti-HIV Nucleoside Reverse Transcriptase Inhibitors.Central role of mitochondria in drug-induced liver injury.Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors.The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development.Differentiation-dependent doxorubicin toxicity on H9c2 cardiomyoblasts.In vitro supplementation with deoxynucleoside monophosphates rescues mitochondrial DNA depletion.Effects of BMS-986094, a Guanosine Nucleotide Analogue, on Mitochondrial DNA Synthesis and Function.Editor's Highlight: Comparative Renal Safety Assessment of the Hepatitis B Drugs, Adefovir, Tenofovir, Telbivudine and Entecavir in Rats.Cumulative incidence and risk factors of creatine kinase elevation associated with telbivudine.A Single Zidovudine (AZT) Administration Delays Hepatic Cell Proliferation by Altering Oxidative State in the Regenerating Rat Liver.AZT-induced oxidative cardiovascular toxicity: attenuation by Mg-supplementation.
P2860
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P2860
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
@ast
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
@en
type
label
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
@ast
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
@en
prefLabel
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
@ast
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
@en
P2093
P2860
P356
P1476
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs.
@en
P2093
Kaleb C Lund
Kendall B Wallace
LaRae L Peterson
P2860
P304
P356
10.1128/AAC.00039-07
P407
P577
2007-04-30T00:00:00Z