Base excision repair and design of small molecule inhibitors of human DNA polymerase β.
about
Base excision repairInstability of CTG repeats is governed by the position of a DNA base lesion through base excision repairHMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblastsReactivity of Nucleic Acid Radicals.Irreversible inhibition of DNA polymerase β by small-molecule mimics of a DNA lesionA 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase βDNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repairRepair of the major lesion resulting from C5'-oxidation of DNA.Quantitative characterization of protein-protein complexes involved in base excision DNA repairDNA base excision repair: a mechanism of trinucleotide repeat expansion.Bypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks.Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis.Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells.Balancing repair and tolerance of DNA damage caused by alkylating agentsSuppression of oxidative phosphorylation in mouse embryonic fibroblast cells deficient in apurinic/apyrimidinic endonuclease.Targeting DNA polymerase ß for therapeutic intervention.Therapeutic intervention by the simultaneous inhibition of DNA repair and type I or type II DNA topoisomerases: one strategy, many outcomes.Generation of a Mono-ubiquitinated PCNA Mimic by Click Chemistry
P2860
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P2860
Base excision repair and design of small molecule inhibitors of human DNA polymerase β.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Base excision repair and design of small molecule inhibitors of human DNA polymerase β.
@ast
Base excision repair and design of small molecule inhibitors of human DNA polymerase β.
@en
type
label
Base excision repair and design of small molecule inhibitors of human DNA polymerase β.
@ast
Base excision repair and design of small molecule inhibitors of human DNA polymerase β.
@en
prefLabel
Base excision repair and design of small molecule inhibitors of human DNA polymerase β.
@ast
Base excision repair and design of small molecule inhibitors of human DNA polymerase β.
@en
P2093
P2860
P1476
Base excision repair and design of small molecule inhibitors of human DNA polymerase β
@en
P2093
Aya Masaoka
David D Shock
Donna F Stefanick
Esther W Hou
Julie K Horton
Kenjiro Asagoshi
Michael J Carrozza
Michelle L Heacock
Nisha A Cavanaugh
Padmini S Kedar
P2860
P2888
P304
P356
10.1007/S00018-010-0489-1
P577
2010-09-16T00:00:00Z