Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells
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Repurposing metformin: an old drug with new tricks in its binding pocketsRepurposing metformin for cancer treatment: current clinical studiesDecoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chainPI3K/Akt/mTOR signaling pathway in cancer stem cells: from basic research to clinical applicationObesity and insulin resistance: an abridged molecular correlationMolecular Connections between Cancer Cell Metabolism and the Tumor MicroenvironmentHypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cellsABT-263 enhances sensitivity to metformin and 2-deoxyglucose in pediatric glioma by promoting apoptotic cell deathResponse of breast cancer cells and cancer stem cells to metformin and hyperthermia alone or combinedRadiation-Induced Glycogen Accumulation Detected by Single Cell Raman Spectroscopy Is Associated with Radioresistance that Can Be Reversed by MetforminInhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A).Perspectives of gene combinations in phenotype presentationMetformin impairs glucose consumption and survival in Calu-1 cells by direct inhibition of hexokinase-II.Metformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation.Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression.Metformin exhibits radiation countermeasures efficacy when used alone or in combination with sulfhydryl containing drugs.Radiosensitization of pancreatic cancer cells by metformin through the AMPK pathway.Molecular radiobiology: the state of the artMetformin and cancer.Glargine safety, diabetes and cancer.LKB1 and AMPK and the cancer-metabolism link - ten years afterImmune-mediated antitumor effect by type 2 diabetes drug, metformin.Reduction behavior induced by HL010183, a metformin derivative against the growth of cutaneous squamous cell carcinoma.Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapyMetformin inhibits growth of human glioblastoma cells and enhances therapeutic responseLoss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1.Metformin Radiosensitizes p53-Deficient Colorectal Cancer Cells through Induction of G2/M Arrest and Inhibition of DNA Repair Proteins.Combined 2-deoxy glucose and metformin improves therapeutic efficacy of sodium-iodide symporter-mediated targeted radioiodine therapy in breast cancer cells.Tumor suppression by resistant maltodextrin, Fibersol-2.Drug Repurposing for Cancer Therapy.Combined regimen of photodynamic therapy mediated by Gallium phthalocyanine chloride and Metformin enhances anti-melanoma efficacyAnti-tumor effects of metformin on head and neck carcinoma cell lines: A systematic reviewMetformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice.Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency.Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK.Metformin induces a senescence-associated gene signature in breast cancer cells.Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer CellsMetformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cellsEvaluation of Diabetic Patients with Breast Cancer Treated with Metformin during Adjuvant Radiotherapy.Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer.
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P2860
Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Metformin kills and radiosensi ...... tially kills cancer stem cells
@ast
Metformin kills and radiosensi ...... tially kills cancer stem cells
@en
type
label
Metformin kills and radiosensi ...... tially kills cancer stem cells
@ast
Metformin kills and radiosensi ...... tially kills cancer stem cells
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prefLabel
Metformin kills and radiosensi ...... tially kills cancer stem cells
@ast
Metformin kills and radiosensi ...... tially kills cancer stem cells
@en
P2093
P2860
P356
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P1476
Metformin kills and radiosensi ...... tially kills cancer stem cells
@en
P2093
Bo-Hwa Choi
Brent Williams
Chang W Song
Heon Joo Park
John Powers
Troy Dos Santos
P2860
P2888
P356
10.1038/SREP00362
P407
P577
2012-04-12T00:00:00Z