Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virus
about
Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanismDevelopment and characterization of positively selected brain-adapted SIV.Unraveling the pathogenesis of HIV peripheral neuropathy: insights from a simian immunodeficiency virus macaque modelChronic alcohol abuse and HIV disease progression: studies with the non-human primate modelRegulation of SIV mac 239 basal long terminal repeat activity and viral replication in macrophages: functional roles of two CCAAT/enhancer-binding protein beta sites in activation and interferon beta-mediated suppression.Accelerated evolution of SIV env within the cerebral compartment in the setting of morphine-dependent rapid disease progressionIsolation and characterization of a neuropathogenic simian immunodeficiency virus derived from a sooty mangabey.Reduced genetic diversity in lymphoid and central nervous system tissues and selection-induced tissue-specific compartmentalization of neuropathogenic SIVsmmFGb during acute infection.CD4-independent, CCR5-dependent simian immunodeficiency virus infection and chemotaxis of human cellsHigh viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis.The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses.In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail.Morphine and rapid disease progression in nonhuman primate model of AIDS: inverse correlation between disease progression and virus evolution.Development and characterization of an in vivo pathogenic molecular clone of equine infectious anemia virus.Short communication: Lack of immune response in rapid progressor morphine-dependent and SIV/SHIV-infected rhesus macaques is correlated with downregulation of TH1 cytokines.Rapid progression to simian AIDS can be accompanied by selection of CD4-independent gp120 variants with impaired ability to bind CD4.Early emergence and selection of a SIV-LTR C/EBP site variant in SIV-infected macaques that increases virus infectivityCharacterization of simian immunodeficiency virus (SIV) that induces SIV encephalitis in rhesus macaques with high frequency: role of TRIM5 and major histocompatibility complex genotypes and early entry to the brainIn vitro and animal models of human immunodeficiency virus infection of the central nervous systemLentiviral neuropathogenesis: comparative neuroinvasion, neurotropism, neurovirulence, and host neurosusceptibilityResting CD4+ T lymphocytes but not thymocytes provide a latent viral reservoir in a simian immunodeficiency virus-Macaca nemestrina model of human immunodeficiency virus type 1-infected patients on highly active antiretroviral therapy.A simian immunodeficiency virus-infected macaque model to study viral reservoirs that persist during highly active antiretroviral therapy.Identification of a subset of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus strains able to exploit an alternative coreceptor on untransformed human brain and lymphoid cells.Expression of simian immunodeficiency virus (SIV) nef in astrocytes during acute and terminal infection and requirement of nef for optimal replication of neurovirulent SIV in vitro.Dysregulation of mitogen-activated protein kinase signaling pathways in simian immunodeficiency virus encephalitis.Induction of innate immune responses by SIV in vivo and in vitro: differential expression and function of RIG-I and MDA5.Variable region 4 of SIV envelope correlates with rapid disease progression in morphine-exposed macaques infected with SIV/SHIV.Human immunodeficiency virus infection of the brain: pitfalls in evaluating infected/affected cell populations.Pathogenesis of simian immunodeficiency virus pneumonia: an immunopathological response to virus.Pathogenesis of SIV encephalitis. Selection and replication of neurovirulent SIVNeuropathology of wild-type and nef-attenuated T cell tropic simian immunodeficiency virus (SIVmac32H) and macrophage tropic neurovirulent SIVmac17E-Fr in cynomolgus macaques.Pathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulenceDynamic evolution of antibody populations in a rhesus macaque infected with attenuated simian immunodeficiency virus identified by surface plasmon resonance.Acquisition of CD4-dependence by CD4-independent SIV passaged in human peripheral blood mononuclear cellsSevere depletion of CD4+ CD25+ regulatory T cells from the intestinal lamina propria but not peripheral blood or lymph nodes during acute simian immunodeficiency virus infection.Rate and severity of HIV-associated dementia (HAD): correlations with Gp41 and iNOSSAMHD1 transcript upregulation during SIV infection of the central nervous system does not associate with reduced viral load.CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strainDerivation and Characterization of a CD4-Independent, Non-CD4-Tropic Simian Immunodeficiency Virus.Enhanced antagonism of BST-2 by a neurovirulent SIV envelope
P2860
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P2860
Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virus
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Molecular and biological chara ...... simian immunodeficiency virus
@ast
Molecular and biological chara ...... simian immunodeficiency virus
@en
type
label
Molecular and biological chara ...... simian immunodeficiency virus
@ast
Molecular and biological chara ...... simian immunodeficiency virus
@en
prefLabel
Molecular and biological chara ...... simian immunodeficiency virus
@ast
Molecular and biological chara ...... simian immunodeficiency virus
@en
P2093
P2860
P1433
P1476
Molecular and biological chara ...... simian immunodeficiency virus
@en
P2093
J E Clements
J L Mankowski
M T Flaherty
P2860
P304
P407
P577
1997-08-01T00:00:00Z