HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency.
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STAT5 in hematopoietic stem cell biology and transplantationMicroRNAs in the Myocyte Enhancer Factor 2 (MEF2)-regulated Gtl2-Dio3 Noncoding RNA Locus Promote Cardiomyocyte Proliferation by Targeting the Transcriptional Coactivator Cited2.Molecular mechanisms of hypoxia in cancer.Metabolic requirements for the maintenance of self-renewing stem cells.Echinomycin protects mice against relapsed acute myeloid leukemia without adverse effect on hematopoietic stem cellsCREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells.HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.Acute loss of Cited2 impairs Nanog expression and decreases self-renewal of mouse embryonic stem cellsCited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 geneNegative regulation of human growth hormone gene expression by insulin is dependent on hypoxia-inducible factor binding in primary non-tumor pituitary cells.Regulation of cell proliferation by hypoxia-inducible factorsHIF-1α inhibition by 2-methoxyestradiol induces cell death via activation of the mitochondrial apoptotic pathway in acute myeloid leukemia.Genetic control of quiescence in hematopoietic stem cells.Cited2, a transcriptional modulator protein, regulates metabolism in murine embryonic stem cells.Cited2 is required for the maintenance of glycolytic metabolism in adult hematopoietic stem cells.Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activityHematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury.The role of hypoxia in stem cell potency and differentiation.Concise review: genetic dissection of hypoxia signaling pathways in normal and leukemic stem cells.Functional Analyses of a Novel CITED2 Nonsynonymous Mutation in Chinese Tibetan Patients with Congenital Heart Disease.Tumor cell vascular mimicry: Novel targeting opportunity in melanoma.Drug resistance and cancer stem cells: the shared but distinct roles of hypoxia-inducible factors HIF1α and HIF2α.Flt3 ligand-eGFP-reporter expression characterizes functionally distinct subpopulations of CD150+ long-term repopulating murine hematopoietic stem cells.Ovarian cancer stem cells: a new target for cancer therapy.Differential expression of transcription factors and inflammation-, ROS-, and cell death-related genes in organotypic cultures in the modiolus, the organ of Corti and the stria vascularis of newborn rats.HIF-1 and its antagonist Cited2: regulators of HSC quiescence.CITED2 restrains pro-inflammatory macrophage activation and response.CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia.
P2860
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P2860
HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
HIF-1α deletion partially resc ...... e caused by Cited2 deficiency.
@ast
HIF-1α deletion partially resc ...... e caused by Cited2 deficiency.
@en
type
label
HIF-1α deletion partially resc ...... e caused by Cited2 deficiency.
@ast
HIF-1α deletion partially resc ...... e caused by Cited2 deficiency.
@en
prefLabel
HIF-1α deletion partially resc ...... e caused by Cited2 deficiency.
@ast
HIF-1α deletion partially resc ...... e caused by Cited2 deficiency.
@en
P2093
P2860
P1433
P1476
HIF-1α deletion partially resc ...... e caused by Cited2 deficiency.
@en
P2093
Cindy Cheng
David Danielpour
Kevin D Bunting
Sally L Dunwoodie
Xiangzi Han
Yu-Chung Yang
Zhengqi Wang
P2860
P304
P356
10.1182/BLOOD-2011-10-387902
P407
P577
2012-02-02T00:00:00Z