Arachidonic acid mobilization in P388D1 macrophages is controlled by two distinct Ca(2+)-dependent phospholipase A2 enzymes
about
P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2Novel group V phospholipase A2 involved in arachidonic acid mobilization in murine P388D1 macrophagesLocalization of group V phospholipase A2 in caveolin-enriched granules in activated P388D1 macrophage-like cells.Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha.Role of group V phospholipase A2 in zymosan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption.Inhibition of calcium-independent phospholipase A2 prevents arachidonic acid incorporation and phospholipid remodeling in P388D1 macrophages.Functional coupling between secretory phospholipase A2 and cyclooxygenase-2 and its regulation by cytosolic group IV phospholipase A2Sorting out the cytokines of asthma.Liberating Chiral Lipid Mediators, Inflammatory Enzymes, and LIPID MAPS from Biological Grease.Altered arachidonate distribution in macrophages from caveolin-1 null mice leading to reduced eicosanoid synthesis.Competitive inhibition of cytosolic Ca2+-dependent phospholipase A2 by acteoside in RBL-2H3 cells.Chitosan-induced phospholipase A2 activation and arachidonic acid mobilization in P388D1 macrophages.Group V phospholipase A(2)-mediated oleic acid mobilization in lipopolysaccharide-stimulated P388D(1) macrophages.Enhancing activity and phospholipase A2 activity: two independent activities present in the enhancing factor molecule.Proinflammatory macrophage-activating properties of the novel phospholipid diacylglycerol pyrophosphate.Regulation of arachidonic acid mobilization in lipopolysaccharide-activated P388D(1) macrophages by adenosine triphosphate.Identification of a third pathway for arachidonic acid mobilization and prostaglandin production in activated P388D1 macrophage-like cells.Effect of Extremely Low Frequency Electromagnetic Fields (EMF) on Phospholipase Activity in the Cultured Cells.Involvement of secretory phospholipase A2 activity in the zymosan rat air pouch model of inflammation.Essential Role for Ethanolamine Plasmalogen Hydrolysis in Bacterial Lipopolysaccharide Priming of Macrophages for Enhanced Arachidonic Acid Release.Blockade of arachidonic acid incorporation into phospholipids induces apoptosis in U937 promonocytic cells.Differential regulation of phospholipase D and phospholipase A2 by protein kinase C in P388D1 macrophages.The distribution and metabolism of arachidonate-containing phospholipids in cellular nuclei.Roles of various phospholipases A2 in providing lysophospholipid acceptors for fatty acid phospholipid incorporation and remodelling.Inhibition of cytosolic phospholipase A2 by annexin I. Specific interaction model and mapping of the interaction site.Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils. Evidence for different arachidonate pools.Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for arInflammatory activation of arachidonic acid signaling in murine P388D1 macrophages via sphingomyelin synthesis.Antisense inhibition of group VI Ca2+-independent phospholipase A2 blocks phospholipid fatty acid remodeling in murine P388D1 macrophages.Calcium-independent phospholipase A2-mediated formation of 1,2-diarachidonoyl-glycerophosphoinositol in monocytes.Calcium-independent phospholipase A2 mediates proliferation of human promonocytic U937 cells.Phospholipase A2 inhibitors in development.Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures.Perturbations in the control of cellular arachidonic acid levels block cell growth and induce apoptosis in HL-60 cells.
P2860
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P2860
Arachidonic acid mobilization in P388D1 macrophages is controlled by two distinct Ca(2+)-dependent phospholipase A2 enzymes
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Arachidonic acid mobilization ...... ndent phospholipase A2 enzymes
@ast
Arachidonic acid mobilization ...... ndent phospholipase A2 enzymes
@en
type
label
Arachidonic acid mobilization ...... ndent phospholipase A2 enzymes
@ast
Arachidonic acid mobilization ...... ndent phospholipase A2 enzymes
@en
prefLabel
Arachidonic acid mobilization ...... ndent phospholipase A2 enzymes
@ast
Arachidonic acid mobilization ...... ndent phospholipase A2 enzymes
@en
P2093
P2860
P356
P1476
Arachidonic acid mobilization ...... ndent phospholipase A2 enzymes
@en
P2093
E A Dennis
I D Bianco
S E Barbour
P2860
P304
11060-11064
P356
10.1073/PNAS.91.23.11060
P407
P577
1994-11-01T00:00:00Z