The cytopathicity of a simian immunodeficiency virus Mne variant is determined by mutations in Gag and Env.
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TRIM5 alpha drives SIVsmm evolution in rhesus macaques.Relative replication capacity of phenotypic SIV variants during primary infections differs with route of inoculation.Non-human primate models for AIDS vaccine research.Changes in simian immunodeficiency virus reverse transcriptase alleles that appear during infection of macaques enhance infectivity and replication in CD4+ T cells.On the relative fitness of early and late stage Simian immunodeficiency virus isolatesA decrease in albumin in early SIV infection is related to viral pathogenicityCoreceptor specificity of temporal variants of simian immunodeficiency virus Mne.Changes in the extracellular envelope glycoprotein of variants that evolve during the course of simian immunodeficiency virus SIVMne infection affect neutralizing antibody recognition, syncytium formation, and macrophage tropism but not replication,A lymph node-derived cytopathic simian immunodeficiency virus Mne variant replicates in nonstimulated peripheral blood mononuclear cells.Mortality among human immunodeficiency virus type 2-positive villagers in rural Guinea-Bissau is correlated with viral genotype.Highly pathogenic simian immunodeficiency virus mne variants that emerge during the course of infection evolve enhanced infectivity and the ability to downregulate CD4 but not class I major histocompatibility complex antigens.Capture and transfer of simian immunodeficiency virus by macaque dendritic cells is enhanced by DC-SIGN.Early- and intermediate-stage variants of simian immunodeficiency virus replicate efficiently in cells lacking CCR5.Simian immunodeficiency virus variants that differ in pathogenicity differ in fitness under rapid cell turnover conditions.Heavily glycosylated, highly fit SIVMne variants continue to diversify and undergo selection after transmission to a new host and they elicit early antibody dependent cellular responses but delayed neutralizing antibody responses.Human immunodeficiency virus evolution towards reduced replicative fitness in vivo and the development of AIDS.
P2860
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P2860
The cytopathicity of a simian immunodeficiency virus Mne variant is determined by mutations in Gag and Env.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The cytopathicity of a simian ...... d by mutations in Gag and Env.
@ast
The cytopathicity of a simian ...... d by mutations in Gag and Env.
@en
type
label
The cytopathicity of a simian ...... d by mutations in Gag and Env.
@ast
The cytopathicity of a simian ...... d by mutations in Gag and Env.
@en
prefLabel
The cytopathicity of a simian ...... d by mutations in Gag and Env.
@ast
The cytopathicity of a simian ...... d by mutations in Gag and Env.
@en
P2860
P1433
P1476
The cytopathicity of a simian ...... d by mutations in Gag and Env.
@en
P2093
J Overbaugh
J T Kimata
P2860
P304
P407
P577
1997-10-01T00:00:00Z