Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses
about
Direct inactivation of human immunodeficiency virus type 1 by a novel small-molecule entry inhibitor, DCM205Antigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cellsSpecific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.Multiple blocks to human immunodeficiency virus type 1 replication in rodent cellsFunctional dissection of CCR5 coreceptor function through the use of CD4-independent simian immunodeficiency virus strainsDifferential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5Kinetic factors control efficiencies of cell entry, efficacies of entry inhibitors, and mechanisms of adaptation of human immunodeficiency virusVariants of human immunodeficiency virus type 1 that efficiently use CCR5 lacking the tyrosine-sulfated amino terminus have adaptive mutations in gp120, including loss of a functional N-glycanChemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells.Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1Frequent substitution polymorphisms in African green monkey CCR5 cluster at critical sites for infections by simian immunodeficiency virus SIVagm, implying ancient virus-host coevolutionCharacterization of novel simian immunodeficiency viruses from red-capped mangabeys from Nigeria (SIVrcmNG409 and -NG411)Adaptive mutations in the V3 loop of gp120 enhance fusogenicity of human immunodeficiency virus type 1 and enable use of a CCR5 coreceptor that lacks the amino-terminal sulfated regionChaperoning G protein-coupled receptors: from cell biology to therapeuticsReversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine.Susceptibilities of simian immunodeficiency virus to protease inhibitorsThe second extracellular loop of CCR5 contains the dominant epitopes for highly potent anti-human immunodeficiency virus monoclonal antibodies.Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.Short Communication: HIV-1 Variants That Use Mouse CCR5 Reveal Critical Interactions of gp120's V3 Crown with CCR5 Extracellular Loop 1gp120 envelope glycoproteins of human immunodeficiency viruses competitively antagonize signaling by coreceptors CXCR4 and CCR5A new monoclonal antibody, mAb 4A12, identifies a role for the glycosaminoglycan (GAG) binding domain of RANTES in the antiviral effect against HIV-1 and intracellular Ca2+ signaling.Soluble complexes of regulated upon activation, normal T cells expressed and secreted (RANTES) and glycosaminoglycans suppress HIV-1 infection but do not induce Ca(2+) signaling.Structure and function of CC-chemokine receptor 5 homologues derived from representative primate species and subspecies of the taxonomic suborders Prosimii and Anthropoidea.The differential sensitivity of human and rhesus macaque CCR5 to small-molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitorsInduction of autoantibodies to mouse CCR5 with recombinant papillomavirus particles.Efavirenz therapy in rhesus macaques infected with a chimera of simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1.Reversible and efficient activation of HIV-1 cell entry by a tyrosine-sulfated peptide dissects endocytic entry and inhibitor mechanisms.A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5CXCR6-Mediated Simian Immunodeficiency Virus SIVagmSab Entry into Sabaeus African Green Monkey Lymphocytes Implicates Widespread Use of Non-CCR5 Pathways in Natural Host Infections.CCR5-Mediated human immunodeficiency virus entry depends on an amino-terminal gp120-binding site and on the conformational integrity of all four extracellular domainsContinued utilization of CCR5 coreceptor by a newly derived T-cell line-adapted isolate of human immunodeficiency virus type 1Polymorphisms of the hepatitis A virus cellular receptor 1 in African green monkey kidney cells result in antigenic variants that do not react with protective monoclonal antibody 190/4.A comprehensive approach to mapping the interacting surfaces of murine amphotropic and feline subgroup B leukemia viruses with their cell surface receptors.Evidence for common structural determinants of human immunodeficiency virus type 1 coreceptor activity provided through functional analysis of CCR5/CXCR4 chimeric coreceptorsCCR5 and CXCR4 usage by non-clade B human immunodeficiency virus type 1 primary isolates.The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment.Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry.An allosteric rheostat in HIV-1 gp120 reduces CCR5 stoichiometry required for membrane fusion and overcomes diverse entry limitations.
P2860
Q24681004-A5082C97-D7D3-45E8-959F-5A8F8C3EEEB2Q27320687-C0CB3EF8-2D9C-417E-AC13-E85FF437FDA9Q28344310-4DCA7B2F-1F8A-4955-BC9E-AA3BD1F29CEAQ29622903-BF14DA5B-F3D8-4C33-A896-134D4E0FA05EQ33603453-B7DD0838-974D-4376-80FA-B390F9E58CC3Q33647409-0457590F-0415-4722-9346-45B292280337Q33647608-41C09C6D-7F36-483E-85FD-94FFC2CE67A5Q33707328-F681EAF2-F9C8-493E-ABE2-DE156D50D1A2Q33707333-4FD79C56-FA3F-4B3F-87A5-E41667D43D89Q33785473-BA8DE3A2-A345-410E-810F-44C824DEDECFQ33808728-4305E512-E8F4-4D81-A36A-A0D3781C4912Q33808920-53BDE517-E6CE-4500-A859-64ECDD903CCEQ33854213-2769E3F7-0B70-4838-A2F8-3BAED4418EE7Q33869873-45EA7BC4-7175-4C74-87C5-D09CC35537A6Q33870292-3BFA29D5-5CB7-4156-922C-56123A59DD3BQ33927508-733D3216-04EC-4883-AF39-FA9338858F63Q34465037-5117BE2D-3A0D-40E8-9B04-38ACCB628117Q34939250-39CAB954-7672-405F-BA24-2DE2A1AC149CQ35758790-13998BC6-697C-4C33-9318-81F94B6D4802Q35985849-5275F2C8-9F86-4222-B380-ABDCB5CF4654Q36078450-83EBDA07-5575-44C2-AA06-878B9C0C7A0EQ36165694-F49F6AB2-1485-43AE-ADA9-45F1399600E4Q36401287-3D61D8E5-F805-4DBD-B30D-5FF2B264D136Q36746649-ED724C2F-DF18-43D1-AD09-E2CCCEDD0562Q36891087-2E697BBD-2E0E-4FD0-8D0D-18F4CDE57F7AQ37092774-6F86E7DA-F0CD-4498-AFC1-62A71BB885DEQ37184404-FC752A5A-98E0-4E1F-A2CB-A3558C7ECC31Q37489188-10063169-8236-4D58-9253-0F04314516ADQ37713831-F2433582-A451-407F-AF42-4A316EFE2E9BQ38341741-6905B4C9-A4DC-446C-8AD7-152C6925434DQ39141518-A1D6ABF4-A8FA-4204-9541-A96637766DA0Q39549575-150C76AE-5B4B-4228-B8CC-E2C4F9D355C0Q39580513-21DC67F5-986A-45A8-A3E3-4BB1FC3685C0Q39582731-0A866098-2D14-414A-8A2F-5F5735380E87Q39588606-ABC57BF6-A432-403F-B35D-EEBB14C141F8Q39605336-9E061377-1042-4EED-A9AD-76A32296F663Q39682772-6262450E-E237-406E-A3D7-9979FB92E459Q41345703-E77E0E70-EBE0-414A-B6DF-A6CBC5EADE03Q41925528-43465B5B-4FAC-4882-B5FF-F969216D05C0Q41996301-68FB58ED-57B3-440F-9F3E-9676F8EF3822
P2860
Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Polymorphisms in the CCR5 gene ...... human immunodeficiency viruses
@ast
Polymorphisms in the CCR5 gene ...... human immunodeficiency viruses
@en
type
label
Polymorphisms in the CCR5 gene ...... human immunodeficiency viruses
@ast
Polymorphisms in the CCR5 gene ...... human immunodeficiency viruses
@en
prefLabel
Polymorphisms in the CCR5 gene ...... human immunodeficiency viruses
@ast
Polymorphisms in the CCR5 gene ...... human immunodeficiency viruses
@en
P2093
P2860
P1433
P1476
Polymorphisms in the CCR5 gene ...... human immunodeficiency viruses
@en
P2093
P2860
P304
P407
P577
1997-11-01T00:00:00Z