Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. - Wikidata - wikimedia - TriplyDB

Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance.

Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance.

http://www.wikidata.org/entity/Q35903509

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Phase II study of NGR-hTNF in combination with doxorubicin in relapsed ovarian cancer patients Myeloid cell signatures in tumor microenvironment predicts therapeutic response in cancer Echoes of the embryo: using the developmental biology toolkit to study cancer Therapeutic potential of chemokine signal inhibition for metastatic breast cancer The Role of Stroma in Tumor Development Pushing tumor cells towards a malignant phenotype: stimuli from the microenvironment, intercellular communications and alternative roads Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis Systems biology of cisplatin resistance: past, present and future Modulation of the tumor microenvironment for cancer treatment: a biomaterials approach Immune escape mechanisms in colorectal cancer pathogenesis and liver metastasis Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy Non-Darwinian dynamics in therapy-induced cancer drug resistance.Genetically engineered mouse models in oncology research and cancer medicine Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decade The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization Evolutionary foundations for cancer biology Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.Interstitial fluid flow in cancer: implications for disease progression and treatment.CD8+ tumor-infiltrating T cells are trapped in the tumor-dendritic cell network.Host matrix modulation by tumor exosomes promotes motility and invasiveness.A bioengineered heterotypic stroma-cancer microenvironment model to study pancreatic ductal adenocarcinoma.Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.Multi-scale optical imaging of the delayed type hypersensitivity reaction attenuated by rapamycin Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations.Validation of a device for the active manipulation of the tumor microenvironment during intravital imaging.Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window.Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial.Microenvironmental regulation of therapeutic response in cancer Peripheral blood lymphocyte/monocyte ratio at the time of first relapse predicts outcome for patients with relapsed or primary refractory diffuse large B-cell lymphoma.Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis Molecular Checkpoint Decisions Made by Subverted Vascular Niche Transform Indolent Tumor Cells into Chemoresistant Cancer Stem Cells Chemotherapy and tumor microenvironment of pancreatic cancer.miR-21 Expression in Cancer Cells may Not Predict Resistance to Adjuvant Trastuzumab in Primary Breast Cancer.Increased expression of CCN2, epithelial membrane antigen, and fibroblast activation protein in hepatocellular carcinoma with fibrous stroma showing aggressive behavior.Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences Tumour cell invasion: an emerging role for basal epithelial cell extrusion.Parallel microfluidic chemosensitivity testing on individual slice cultures.Breast cancer: coordinated regulation of CCL2 secretion by intracellular glycosaminoglycans and chemokine motifs.

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Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance.

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J.CCR.2012.02.017

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Andrew J Ewald

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P2860

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

DNA damage-mediated induction of a chemoresistant niche

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

Dynamic in vivo imaging and cell tracking using a histone fluorescent protein fusion in mice

Calreticulin exposure dictates the immunogenicity of cancer cell death

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

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