Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs
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iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types.Taming Human Genetic Variability: Transcriptomic Meta-Analysis Guides the Experimental Design and Interpretation of iPSC-Based Disease Modeling.Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression SignaturevariancePartition: interpreting drivers of variation in complex gene expression studies.Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.Patient-derived induced pluripotent stem cells in cancer research and precision oncology.Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.Capturing Human Naïve Pluripotency in the Embryo and in the Dish.Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells.Common genetic variation drives molecular heterogeneity in human iPSCs.Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs.Impact of regulatory variation across human iPSCs and differentiated cells.Aberrant DNA Methylation in Human iPSCs Associates with MYC-Binding Motifs in a Clone-Specific Manner Independent of Genetics.Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells.[Leukocyte count of puerperal sows].New considerations for hiPSC-based models of neuropsychiatric disorders.Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects.STEM CELLS. Reprogrammed cells leave their past lives behind.From the Psychiatrist's Couch to Induced Pluripotent Stem Cells: Bipolar Disease in a Dish.Global variation in gene expression and the value of diverse sampling.Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs.Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes.A Comparative Assessment of Human and Chimpanzee iPSC-derived Cardiomyocytes with Primary Heart TissuesTracing Early Neurodevelopment in Schizophrenia with Induced Pluripotent Stem Cells
P2860
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P2860
Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs
description
2016 nî lūn-bûn
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2016年の論文
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2016年論文
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2016年論文
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2016年論文
@zh-hk
2016年論文
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2016年論文
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2016年论文
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2016年论文
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2016年论文
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name
Genetic Variation, Not Cell Ty ...... egulatory Differences in iPSCs
@ast
Genetic Variation, Not Cell Ty ...... egulatory Differences in iPSCs
@en
type
label
Genetic Variation, Not Cell Ty ...... egulatory Differences in iPSCs
@ast
Genetic Variation, Not Cell Ty ...... egulatory Differences in iPSCs
@en
prefLabel
Genetic Variation, Not Cell Ty ...... egulatory Differences in iPSCs
@ast
Genetic Variation, Not Cell Ty ...... egulatory Differences in iPSCs
@en
P2093
P2860
P1433
P1476
Genetic Variation, Not Cell Ty ...... egulatory Differences in iPSCs
@en
P2093
Bryan J Pavlovic
Courtney K Burrows
Jonathan K Pritchard
Kristen Patterson
Nicholas E Banovich
Yoav Gilad
P2860
P304
P356
10.1371/JOURNAL.PGEN.1005793
P577
2016-01-26T00:00:00Z