Highly resistant HIV-1 proteases and strategies for their inhibition. - Wikidata - wikimedia - TriplyDB

Highly resistant HIV-1 proteases and strategies for their inhibition.

Highly resistant HIV-1 proteases and strategies for their inhibition.

http://www.wikidata.org/entity/Q35907004

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Effects of Hinge Region Natural Polymorphisms on Human Immunodeficiency Virus-1 Protease Structure, Dynamics and Drug-Pressure Evolution Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics Automated prediction of HIV drug resistance from genotype data Conformational variation of an extreme drug resistant mutant of HIV protease.Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site.Binding of Clinical Inhibitors to a Model Precursor of a Rationally Selected Multidrug Resistant HIV-1 Protease Is Significantly Weaker Than That to the Released Mature Enzyme Investigational protease inhibitors as antiretroviral therapies.Decoding HIV resistance: from genotype to therapy.Room Temperature Neutron Crystallography of Drug Resistant HIV-1 Protease Uncovers Limitations of X-ray Structural Analysis at 100 K.Mutations Proximal to Sites of Autoproteolysis and the α-Helix That Co-evolve under Drug Pressure Modulate the Autoprocessing and Vitality of HIV-1 Protease.Can we design drugs for HIV/AIDS that are less susceptible to resistance?Inhibition of the precursor and mature forms of HIV-1 protease as a tool for drug evaluation.

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Highly resistant HIV-1 proteases and strategies for their inhibition.

http://www.wikidata.org/entity/Q35907004

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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name

Highly resistant HIV-1 proteases and strategies for their inhibition.

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Highly resistant HIV-1 proteases and strategies for their inhibition.

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Highly resistant HIV-1 proteases and strategies for their inhibition.

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Highly resistant HIV-1 proteases and strategies for their inhibition.

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Highly resistant HIV-1 proteases and strategies for their inhibition.

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Highly resistant HIV-1 proteases and strategies for their inhibition.

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Future Medicinal Chemistry

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Highly resistant HIV-1 proteases and strategies for their inhibition

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Daniel W Kneller

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Irene T Weber

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P2860

The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles

Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region

Targeting the open-flap conformation of HIV-1 protease with pyrrolidine-based inhibitors

Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir

Fragment-Based Screen against HIV Protease

Probing Multidrug-Resistance and Protein-Ligand Interactions with Oxatricyclic Designed Ligands in HIV-1 Protease Inhibitors

The L76V Drug Resistance Mutation Decreases the Dimer Stability and Rate of Autoprocessing of HIV-1 Protease by Reducing Internal Hydrophobic Contacts

Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants

Two solutions for the same problem: multiple binding modes of pyrrolidine-based HIV-1 protease inhibitors

The higher barrier of darunavir and tipranavir resistance for HIV-1 protease

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1023-1038

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scholarly article

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10.4155/FMC.15.44

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8

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7

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Andres Wong-Sam

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2015-01-01T00:00:00Z

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26062399

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4521605

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