Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells. - Wikidata - wikimedia - TriplyDB

Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells.

Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells.

http://www.wikidata.org/entity/Q35907038

about

Novel epigallocatechin gallate analogs as potential anticancer agents: a patent review (2009 - present)Regulation of AMP-activated protein kinase by natural and synthetic activators Polyphenols as Modulator of Oxidative Stress in Cancer Disease: New Therapeutic Strategies New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate Cancer Stem and Progenitor-Like Cells as Pharmacological Targets in Breast Cancer Treatment Computational and Biochemical Discovery of RSK2 as a Novel Target for Epigallocatechin Gallate (EGCG)Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells Liver kinase B1 regulates the centrosome via PLK1.EGCG inhibits the growth and tumorigenicity of nasopharyngeal tumor-initiating cells through attenuation of STAT3 activation Epigallocathechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines Genistein suppresses LPS-induced inflammatory response through inhibiting NF-κB following AMP kinase activation in RAW 264.7 macrophages.Anti-inflammatory effect of Prunus yedoensis through inhibition of nuclear factor-κB in macrophages Overexpression of miR-126 sensitizes osteosarcoma cells to apoptosis induced by epigallocatechin-3-gallate.EGCG attenuates autoimmune arthritis by inhibition of STAT3 and HIF-1α with Th17/Treg control.Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases Epigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampal autophagic flux Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death Targeting the AMP-Activated Protein Kinase for Cancer Prevention and Therapy.Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: a potential role for reducing lipid accumulation.The interplay of AMP-activated protein kinase and androgen receptor in prostate cancer cells.AMP-activated protein kinase and energy balance in breast cancer.Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.Catechin prodrugs and analogs: a new array of chemical entities with improved pharmacological and pharmacokinetic properties.Green tea catechins: a fresh flavor to anticancer therapy.AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole-body levels.Activators of AMPK: not just for type II diabetes.Lessons from Nature: Sources and Strategies for Developing AMPK Activators for Cancer Chemotherapeutics Delivery of therapeutics using nanocarriers for targeting cancer cells and cancer stem cells.Natural product-based therapeutics for the treatment of cancer stem cells: a patent review (2010 - 2013).Food systems approach to cancer prevention.Standardized Extract from Caesalpinia spinosa is Cytotoxic Over Cancer Stem Cells and Enhance Anticancer Activity of Doxorubicin.Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy A Metabolic Inhibitory Cocktail for Grave Cancers: Metformin, Pioglitazone and Lithium Combination in Treatment of Pancreatic Cancer and Glioblastoma Multiforme.(-)-Epigallocatechin-3-gallate inhibits nasopharyngeal cancer stem cell self-renewal and migration and reverses the epithelial-mesenchymal transition via NF-κB p65 inactivation.Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review.EGCG inhibits properties of glioma stem-like cells and synergizes with temozolomide through downregulation of P-glycoprotein inhibition.Concise Review: Emerging Drugs Targeting Epithelial Cancer Stem-Like Cells.Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.Nanocarrier based approaches for targeting breast cancer stem cells.Bioavailability of Tea Catechins and Its Improvement

P2860

Q24595211-2DDDA1A9-0B56-41D3-9800-7312E5880D77 Q26767334-2F7E5DCD-A39D-409A-B31B-539FC6C8AD3A Q26822819-D34B06E4-4A54-47F9-B511-EC4C755D92BC Q27012831-CF4BE538-CB6A-4F3D-B6EE-DE712C820355 Q27024816-AB1683EA-0256-4E89-8F4E-3E7A081A9305 Q28548416-11FFC9F6-4286-43A6-A039-56DD3D29F717 Q31138996-D5E0F3B7-C8FA-45F1-914E-23E383431A4F Q33654208-8A2B1FF2-671E-4865-B826-7907A41460AC Q33803015-ED84EEAA-BDFA-4D07-B38C-EC6D31E7FEB1 Q34461440-04AC2727-35C6-434B-AA01-DE2204C92CDE Q34541665-2BCB48B1-9ECF-405F-89CD-A5D080D7FBBB Q34695867-3FBE7A83-91FA-448E-B689-FC5660C93D62 Q34990949-F10E0708-337F-45F2-B8B0-15EBF7D772DC Q35099449-00F06F07-1EE1-4E0C-8C9B-4D22AC57D1D6 Q35224775-9EF836C6-60D3-477D-83CC-77C7ECE37272 Q35417622-8993B398-8647-4771-99FD-39F7B56BF1D4 Q36988531-57E87A5C-2368-4AC7-93C0-5DB731C07CE4 Q37011502-689E150B-A956-4D91-A077-2E90049F5F9F Q37311969-B8D648FC-B9CF-4334-BAD0-CAAB106141CB Q37626493-634B7389-54A0-44A2-AC6E-D2859688046B Q37685196-2C406C51-0E06-493F-852F-5730D2A9FA52 Q37694816-CEDE25CD-248F-425F-A4CF-6C04A8ADCF22 Q38140631-B8A07DF4-D17F-40DE-9838-DFF3F6C3D7CA Q38147993-3E603170-6A6A-4D84-AC71-D5E33349967B Q38213662-F9BF2122-1248-450A-8DFC-DE91CDFCB3AA Q38243893-2466FD45-9B99-4F56-B13D-ED9C75EB343E Q38289532-98472B48-938C-42AE-8053-AFF5689D1D95 Q38322466-A14BA13E-B6B4-4742-A72C-3689E94F844B Q38367692-0862BC8A-AA78-4FA4-8F67-3DD59966D332 Q38550682-CE3B1311-3228-46BB-8263-A701E757471E Q38730830-A97417EE-FAF1-4746-A104-8DA4BF1AFE70 Q38823095-05EDC86B-BE39-4676-A4FC-8409A91BC63E Q38885892-26C54579-F6E5-4A8C-974E-E0FB7BA9C5FB Q38930822-F03990DB-187D-4937-AD55-C8D1D7ACE476 Q38958946-9721FE2C-4F19-43EB-9B13-26DBB42C59A8 Q38961466-215CCA7A-CF11-4B0F-B2FB-3A4EB2770DD1 Q39112034-C67D72E6-BC15-4EA3-B170-B9CF2B5043BF Q39370677-D4801A42-BF9E-42C2-B43B-2CFEC826B83E Q48209273-A057C2B2-E0D5-4CC6-9B3B-C2D6C296D3AE Q58696704-3BF575B1-0633-4C43-A60B-8F42775AEE7D

P2860

Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells.

http://www.wikidata.org/entity/Q35907038

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Novel epigallocatechin gallate ...... and target cancer stem cells.

@ast

Novel epigallocatechin gallate ...... and target cancer stem cells.

@en

type

label

Novel epigallocatechin gallate ...... and target cancer stem cells.

@ast

Novel epigallocatechin gallate ...... and target cancer stem cells.

@en

prefLabel

Novel epigallocatechin gallate ...... and target cancer stem cells.

@ast

Novel epigallocatechin gallate ...... and target cancer stem cells.

@en

P1433

Q35907038-BFDABF8C-1136-4A9D-938E-3696B6AB17A4

P1476

Q35907038-4C19F43C-08BE-4381-BC0F-3085019C357F

P2093

Q35907038-613A2C3E-F203-49BD-B2DE-B581224265BD

Q35907038-B816A4D0-43E9-447B-9808-926AE7EB7D65

Q35907038-C59C63F3-BD54-4674-AB1E-3EC5110F044F

Q35907038-DDEC0B29-1B17-41B8-8FF7-42CCE50CE28D

Q35907038-EDAC4A3C-A67A-4932-A5F2-07263B7F65AD

P2860

Q35907038-019836AD-10FA-4BAC-9D6B-5700468679B9

Q35907038-029EB2C8-9F39-4CB4-AE66-93ABEA585CC5

Q35907038-070AE292-AF2F-452A-8484-2F2E59AE9BC2

Q35907038-07279A2C-0530-4C82-9026-52730C90418B

Q35907038-09F91FF4-4CAC-40D0-9945-DC6AF6ED5744

Q35907038-0C7D14F0-F4ED-4E7D-A95C-F8EFAC1363F9

Q35907038-132032AF-CB06-4C55-A9B9-10F82C955F7E

Q35907038-16C0606B-3A36-4624-B846-F64BFE1451DD

Q35907038-22D9B2E6-26E4-476B-8D5D-02602B3D66D3

Q35907038-30A370F9-D2DB-43D3-829B-9740079E3EB4

P304

Q35907038-F15E73C9-DD7D-40A7-BA6F-B0CF37C891E4

P31

Q35907038-05401DFA-6340-41D1-ADB1-0442B4F67C0B

P356

Q35907038-3B1ED14C-A29E-4AE6-B782-57A85B9646B8

P407

Q35907038-20303C10-B396-4450-B51C-3D127766AE48

P433

Q35907038-6518C0EC-1862-47C9-A644-EC973D431908

P478

Q35907038-168A0E0F-FE22-4F5C-8726-36C3677DE50A

P577

Q35907038-A5A3DB96-D470-42CB-A6B9-86C72A1143B8

P5875

Q35907038-2EAFB879-7BE4-4327-B364-35C8BF6D76A2

P698

Q35907038-5D562F91-16E3-4FEC-80A2-0BC6FB6A578B

P932

Q35907038-924A794C-4D6D-4AF9-B30C-67C37EB83F4E

P356

J.BMC.2012.03.002

P1433

Bioorganic & Medicinal Chemistry

P1476

Novel epigallocatechin gallate ...... and target cancer stem cells.

@en

P2093

Di Chen

http://www.w3.org/2001/XMLSchema#string

Q Ping Dou

http://www.w3.org/2001/XMLSchema#string

Qiuzhi Cui

http://www.w3.org/2001/XMLSchema#string

Sreedhar Pamu

http://www.w3.org/2001/XMLSchema#string

Tak Hang Chan

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis for AMP binding to mammalian AMP-activated protein kinase

AMPK phosphorylation of raptor mediates a metabolic checkpoint

CD44 cell adhesion molecules

A para-amino substituent on the D-ring of green tea polyphenol epigallocatechin-3-gallate as a novel proteasome inhibitor and cancer cell apoptosis inducer

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Prospective identification of tumorigenic breast cancer cells

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Metformin induces unique biological and molecular responses in triple negative breast cancer cells

Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells

P304

3031-3037

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.BMC.2012.03.002

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

P577

2012-03-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

223994587

http://www.w3.org/2001/XMLSchema#string

P698

22459208

http://www.w3.org/2001/XMLSchema#string

P932

3334407

http://www.w3.org/2001/XMLSchema#string