Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
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Functions of TET Proteins in Hematopoietic TransformationRole of TET enzymes in DNA methylation, development, and cancer5'-Hydroxymethylcytosine Precedes Loss of CpG Methylation in Enhancers and Genes Undergoing Activation in Cardiomyocyte MaturationBase-resolution profiling of active DNA demethylation using MAB-seq and caMAB-seqInfluence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerasesMAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myelomaTALEored Epigenetics: A DNA-Binding Scaffold for Programmable Epigenome Editing and Analysis.Charting oxidized methylcytosines at base resolution.Acute loss of TET function results in aggressive myeloid cancer in mice.Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In VitroDNA methylation and hydroxymethylation in hematologic differentiation and transformation.TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicingSingle-Cell Quantification of Cytosine Modifications by Hyperspectral Dark-Field Imaging.A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways.The Impact of DNA Methylation in Hematopoietic Malignancies.Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitutionInterplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cellsRNA polymerase II acts as a selective sensor for DNA lesions and endogenous DNA modificationsAnalysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study.RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motifElucidation of the Dynamics of Transcription Elongation by RNA Polymerase II using Kinetic Network ModelsMechanism of transcription-coupled DNA modification recognition.Tet2 Catalyzes Stepwise 5-Methylcytosine Oxidation by an Iterative and de novo Mechanism.RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.5-Formylcytosine does not change the global structure of DNA.Transcription factor trapping by RNA in gene regulatory elementsThe expanding scope and impact of epigenetic cytosine modifications.Are there specific readers of oxidized 5-methylcytosine bases?The Structural Basis of Transcription: 10 Years After the Nobel Prize in Chemistry.Structure and Function of TET Enzymes.DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications.DNA demethylation pathways: Additional players and regulators.Alternative roles for oxidized mCs and TETs.Epigenetic modification of nucleic acids: from basic studies to medical applications.O-GlcNAcylation and chromatin remodeling in mammals: an up-to-date overview.TET family dioxygenases and DNA demethylation in stem cells and cancers.Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry.
P2860
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P2860
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
@ast
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
@en
type
label
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
@ast
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
@en
prefLabel
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
@ast
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
@en
P2093
P2860
P356
P1433
P1476
Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
@en
P2093
Jenny Chong
Lanfeng Wang
Liang Chen
Xiang-Dong Fu
P2860
P2888
P304
P356
10.1038/NATURE14482
P407
P50
P577
2015-06-29T00:00:00Z
P5875
P6179
1002166162