Combinatorial promoter design for engineering noisy gene expression
about
Modeling structure-function relationships in synthetic DNA sequences using attribute grammarsNature, nurture, or chance: stochastic gene expression and its consequencesTuning the dials of Synthetic BiologyThe incoherent feed-forward loop can generate non-monotonic input functions for genesWriting DNA with GenoCADIntroduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiaeEffect of promoter architecture on the cell-to-cell variability in gene expressionDesign principles of a genetic alarm clockNew measurement methods of network robustness and response ability via microarray dataDistance and helical phase dependence of synergistic transcription activation in cis-regulatory moduleProgramming cells: towards an automated 'Genetic Compiler'Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data.Targeted development of registries of biological partsAnalysis of combinatorial cis-regulation in synthetic and genomic promotersDiversity-based, model-guided construction of synthetic gene networks with predicted functions.Robustness and evolvability in natural chemical resistance: identification of novel systems properties, biochemical mechanisms and regulatory interactions.TATA is a modular component of synthetic promoters.An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noiseA novel sequence and context based method for promoter recognition.Tuning and controlling gene expression noise in synthetic gene networks.Stochastic sequence-level model of coupled transcription and translation in prokaryotes.Noise-driven heterogeneity in the rate of genetic-variant generation as a basis for evolvability.Robust synthetic gene network design via library-based search method.Computational design of synthetic regulatory networks from a genetic library to characterize the designability of dynamical behaviorsGenetic flexibility of regulatory networksThe transition between stochastic and deterministic behavior in an excitable gene circuit.Controlling promoter strength and regulation in Saccharomyces cerevisiae using synthetic hybrid promoters.Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters.A synthetic biology framework for programming eukaryotic transcription functions.Probing the effect of promoters on noise in gene expression using thousands of designed sequences.How does evolution tune biological noise?Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects.Fundamental relationship between operon organization and gene expressionA computational pipeline for identifying kinetic motifs to aid in the design and improvement of synthetic gene circuits.Design and characterization of a dual-mode promoter with activation and repression capability for tuning gene expression in yeastUsing dynamic noise propagation to infer causal regulatory relationships in biochemical networks.Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters.Expression-level dependent perturbation of cell proteostasis and nuclear morphology by aggregation-prone polyglutamine proteins.Robust design of biological circuits: evolutionary systems biology approachA common repressor pool results in indeterminacy of extrinsic noise
P2860
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P2860
Combinatorial promoter design for engineering noisy gene expression
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Combinatorial promoter design for engineering noisy gene expression
@ast
Combinatorial promoter design for engineering noisy gene expression
@en
type
label
Combinatorial promoter design for engineering noisy gene expression
@ast
Combinatorial promoter design for engineering noisy gene expression
@en
prefLabel
Combinatorial promoter design for engineering noisy gene expression
@ast
Combinatorial promoter design for engineering noisy gene expression
@en
P2860
P356
P1476
Combinatorial promoter design for engineering noisy gene expression
@en
P2093
James J Collins
Kevin F Murphy
P2860
P304
12726-12731
P356
10.1073/PNAS.0608451104
P407
P577
2007-07-24T00:00:00Z