The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.
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Akt3 is responsible for the survival and proliferation of embryonic stem cellsInhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells.The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction.Genetic deletion and pharmacological inhibition of Akt1 isoform attenuates bladder cancer cell proliferation, motility and invasion.Loss of MiR-664 Expression Enhances Cutaneous Malignant Melanoma Proliferation by Upregulating PLP2DW-F5: A novel formulation against malignant melanoma from Wrightia tinctoriaBMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistanceVaricella-zoster virus ORF12 protein activates the phosphatidylinositol 3-kinase/Akt pathway to regulate cell cycle progression.Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma.The Hydrogen Sulfide Releasing Molecule Acetyl Deacylasadisulfide Inhibits Metastatic Melanoma.PP2A-Mediated Anticancer Therapy.The role of the dysfunctional akt-related pathway in cancer: establishment and maintenance of a malignant cell phenotype, resistance to therapy, and future strategies for drug development.Transcription addiction: can we garner the Yin and Yang functions of E2F1 for cancer therapy?MAPK pathway inhibition in melanoma: resistance three ways.Activators of AMPK: not just for type II diabetes.Current position of TNF-α in melanomagenesis.Nanoparticle-Based Celecoxib and Plumbagin for the Synergistic Treatment of Melanoma.Anthocyanins from black rice (Oryza sativa L.) demonstrate antimetastatic properties by reducing MMPs and NF-κB expressions in human oral cancer CAL 27 cells.The novel PI3 kinase inhibitor, BAY 80-6946, impairs melanoma growth in vivo and in vitro.Targeting protein kinase-b3 (akt3) signaling in melanoma.Celastrol inhibits growth and induces apoptotic cell death in melanoma cells via the activation ROS-dependent mitochondrial pathway and the suppression of PI3K/AKT signaling.Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer.Analysis of TSC1 mutation spectrum in mucosal melanoma.A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway.Repression of Akt3 gene transcription by the tumor suppressor RIZ1.Conformation-dependent binding of a Tetrastatin peptide to αvβ3 integrin decreases melanoma progression through FAK/PI3K/Akt pathway inhibition.Exploring major signaling cascades in melanomagenesis: a rationale route for targetted skin cancer therapy
P2860
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P2860
The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.
@ast
The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.
@en
type
label
The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.
@ast
The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.
@en
prefLabel
The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.
@ast
The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.
@en
P2860
P356
P1476
The Akt signaling pathway: an emerging therapeutic target in malignant melanoma
@en
P2093
Paul J Mosca
SubbaRao V Madhunapantula
P2860
P304
P356
10.4161/CBT.12.12.18442
P577
2011-12-15T00:00:00Z