Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8(+) T cells and activating Foxp3(+) regulatory T cells.
about
Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in miceRegulatory dendritic cells for immunotherapy in immunologic diseasesImmunoregulatory molecules are master regulators of inflammation during the immune responseNovel concept of iSALT (inducible skin-associated lymphoid tissue) in the elicitation of allergic contact dermatitisNovel insights into the role of immune cells in skin and inducible skin-associated lymphoid tissue (iSALT)Hapten-induced contact hypersensitivity, autoimmune reactions, and tumor regression: plausibility of mediating antitumor immunityThe Skin as a Route of Allergen Exposure: Part II. Allergens and Role of the Microbiome and Environmental Exposures.Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance.Tailored immunity by skin antigen-presenting cells.Dendritic cells from oral cavity induce Foxp3(+) regulatory T cells upon antigen stimulation.Specific roles for dendritic cell subsets during initiation and progression of psoriasis.ICOS regulates the generation and function of human CD4+ Treg in a CTLA-4 dependent manner.Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the SkinPhenotypic and Functional Properties of Human Steady State CD14+ and CD1a+ Antigen Presenting Cells and Epidermal Langerhans CellsEpidermal Langerhans cells tune skin reactivity to contact allergens.Skin dendritic cells induce follicular helper T cells and protective humoral immune responses.Tolerogenic dendritic cells and their applications in transplantationTrial watch: Dendritic cell-based interventions for cancer therapySpecialized role of migratory dendritic cells in peripheral tolerance induction.Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer.Can we produce true tolerance in patients with food allergy?TIM-4 is differentially expressed in the distinct subsets of dendritic cells in skin and skin-draining lymph nodes and controls skin Langerhans cell homeostasis.Shedding light on cutaneous innate immune responses: the intravital microscopy approach.Dendritic cells in the periphery control antigen-specific natural and induced regulatory T cells.Migratory conventional dendritic cells in the induction of peripheral T cell tolerance.Human dendritic cells - stars in the skin.The origins and functions of dendritic cells and macrophages in the skin.Immunology of metal allergies.Cutaneous immunology: basics and new concepts.Immunology and genetics of tumour necrosis factor in allergic contact dermatitis.Emerging Skin T-Cell Functions in Response to Environmental InsultsThe XS106 cell: a Langerhans' cell surrogate with a selective type 2 phenotype.Dendritic cell migration in health and disease.Skin Immunity.Interplay between barrier epithelial cells and dendritic cells in allergic sensitization through the lung and the skin.Dendritic Cells and Their Role in Allergy: Uptake, Proteolytic Processing and Presentation of Allergens.Neoantigen Expression in Steady-State Langerhans Cells Induces CTL Tolerance.Modular expression analysis reveals functional conservation between human Langerhans cells and mouse cross-priming dendritic cells.Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1(+) DCs in mouse and human and distinguishes them from Langerhans cells
P2860
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P2860
Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8(+) T cells and activating Foxp3(+) regulatory T cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Langerhans cells protect from ...... g Foxp3(+) regulatory T cells.
@ast
Langerhans cells protect from ...... g Foxp3(+) regulatory T cells.
@en
type
label
Langerhans cells protect from ...... g Foxp3(+) regulatory T cells.
@ast
Langerhans cells protect from ...... g Foxp3(+) regulatory T cells.
@en
prefLabel
Langerhans cells protect from ...... g Foxp3(+) regulatory T cells.
@ast
Langerhans cells protect from ...... g Foxp3(+) regulatory T cells.
@en
P2093
P2860
P50
P356
P1476
Langerhans cells protect from ...... ng Foxp3(+) regulatory T cells
@en
P2093
Bertrand Dubois
Dominique Kaiserlian
Fériel Hacini-Rachinel
Morgan Taillardet
Tim Sparwasser
P2860
P304
P356
10.1172/JCI59725
P407
P577
2012-04-23T00:00:00Z