Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
about
Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism?How selenium has altered our understanding of the genetic codeA novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAsSelenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFαMethylation of the ribosyl moiety at position 34 of selenocysteine tRNA[Ser]Sec is governed by both primary and tertiary structure.Supramolecular complexes mediate selenocysteine incorporation in vivoEvidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machineryThe RNA-binding protein Secisbp2 differentially modulates UGA codon reassignment and RNA decay.Efficiency of mammalian selenocysteine incorporation.Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA.Selenoproteins: molecular pathways and physiological roles.Nonsense-mediated decay factors are involved in the regulation of selenoprotein mRNA levels during selenium deficiencySelective inhibition of selenocysteine tRNA maturation and selenoprotein synthesis in transgenic mice expressing isopentenyladenosine-deficient selenocysteine tRNA.From one amino acid to another: tRNA-dependent amino acid biosynthesisOverproduction of selenocysteine tRNA in Chinese hamster ovary cells following transfection of the mouse tRNA[Ser]Sec geneSelective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium.Editing does not exist for mammalian selenocysteine tRNAs.Inhibition of selenocysteine tRNA[Ser]Sec aminoacylation provides evidence that aminoacylation is required for regulatory methylation of this tRNA.A recoding element that stimulates decoding of UGA codons by Sec tRNA[Ser]SecDietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice.Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp).Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development.Loss of housekeeping selenoprotein expression in mouse liver modulates lipoprotein metabolismMutation in human selenocysteine transfer RNA selectively disrupts selenoprotein synthesis.Amino acid modifications on tRNA.Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteine.Human cells have a limited set of tRNA anticodon loop substrates of the tRNA isopentenyltransferase TRIT1 tumor suppressor.tRNASer(CGA) differentially regulates expression of wild-type and codon-modified papillomavirus L1 genes.Some properties of murine selenocysteine synthase.Selenoproteins and oxidative stress-induced inflammatory tumorigenesis in the gut.Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position.A regulatory role for Sec tRNA[Ser]Sec in selenoprotein synthesis.Differential regulation of glutathione peroxidase by selenomethionine and hyperoxia in endothelial cells.Selenoproteins in Tumorigenesis and Cancer Progression.Chemical Speciation of Selenium and Mercury as Determinant of Their Neurotoxicity.Selenocysteine tRNA[Ser]Sec, the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing.On elongation factor eEFSec, its role and mechanism during selenium incorporation into nascent selenoproteins.Selenium metabolism in Drosophila. Characterization of the selenocysteine tRNA population.Selenium-Dependent Antioxidant Enzymes: Actions and Properties of Selenoproteins.The utilization of selenocysteine-tRNA[Ser]Sec isoforms is regulated in part at the level of translation in vitro.
P2860
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P2860
Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
@ast
Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
@en
type
label
Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
@ast
Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
@en
prefLabel
Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
@ast
Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
@en
P2093
P2860
P356
P1476
Selenium induces changes in the selenocysteine tRNA[Ser]Sec population in mammalian cells
@en
P2093
P2860
P304
P356
10.1093/NAR/19.4.939
P407
P577
1991-02-01T00:00:00Z