Design of protein membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor V
about
Computational methods in drug discoveryCrystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.Trp2313-His2315 of Factor VIII C2 Domain Is Involved in Membrane Binding: STRUCTURE OF A COMPLEX BETWEEN THE C2 DOMAIN AND AN INHIBITOR OF MEMBRANE BINDINGEmerging methodologies to investigate lipid-protein interactionsTollip or not Tollip: what are the evolving questions behind it?Rational design of small-molecule stabilizers of spermine synthase dimer by virtual screening and free energy-based approachMS-DOCK: accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening.Receptor-Based Discovery of a Plasmalemmal Monoamine Transporter Inhibitor via High Throughput Docking and Pharmacophore Modeling.Cellular and molecular interactions of phosphoinositides and peripheral proteinsConservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.Screening Outside the Catalytic Site: Inhibition of Macromolecular Inter-actions Through Structure-Based Virtual Ligand Screening Experiments.Cellular membranes and lipid-binding domains as attractive targets for drug development.Lipid binding domains: more than simple lipid effectors.Computational Biology and Chemistry in MTi: Emphasis on the Prediction of Some ADMET Properties.Identification of small-molecule inhibitors against SecA by structure-based virtual ligand screening.Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.Optimization of compound ranking for structure-based virtual ligand screening using an established FRED-Surflex consensus approach.Three-dimensional structure generators of drug-like compounds: DG-AMMOS, an open-source package.Designing a ligand for pharmaceutical purposesIn Silico ADME/Tox Predictions
P2860
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P2860
Design of protein membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor V
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Design of protein membrane int ...... with the C2 domain of factor V
@ast
Design of protein membrane int ...... with the C2 domain of factor V
@en
type
label
Design of protein membrane int ...... with the C2 domain of factor V
@ast
Design of protein membrane int ...... with the C2 domain of factor V
@en
prefLabel
Design of protein membrane int ...... with the C2 domain of factor V
@ast
Design of protein membrane int ...... with the C2 domain of factor V
@en
P2093
P2860
P50
P356
P1476
Design of protein membrane int ...... with the C2 domain of factor V
@en
P2093
Bruno O Villoutreix
Gerry A F Nicolaes
Jan Rosing
Kenneth Segers
Rainer Fischer
P2860
P304
12697-12702
P356
10.1073/PNAS.0701051104
P407
P577
2007-07-23T00:00:00Z