Calmodulin kinase II constitutively binds, phosphorylates, and inhibits brush border Na+/H+ exchanger 3 (NHE3) by a NHERF2 protein-dependent process.
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Regulation of Intestinal Glucose Absorption by Ion Channels and TransportersCyclic GMP kinase II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites: identification of a multifunctional phosphorylation siteRegulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2.AKT and GSK-3 are necessary for direct ezrin binding to NHE3 as part of a C-terminal stimulatory complex: role of a novel Ser-rich NHE3 C-terminal motif in NHE3 activity and trafficking.PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs.Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes.Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca(2+), cGMP and lysophosphatidic acid.
P2860
Q26771126-7C4D7FFD-9E9E-4A37-8190-D222ADA006F2Q35002780-8BCE7322-7848-4C99-820E-90C3356F0415Q35813335-62A13C8D-4B4D-4960-994F-491E2A2FC6EDQ37608417-1E2A1576-2A3D-42C2-9A80-8D4BCA3F4F53Q38712681-5591ABED-1EFD-461D-9E03-90025F21BDCEQ41001492-BAF6E011-C2E4-4740-BEE3-3B5B116951EFQ42514629-303686D5-C68B-4150-A199-6E142A486876
P2860
Calmodulin kinase II constitutively binds, phosphorylates, and inhibits brush border Na+/H+ exchanger 3 (NHE3) by a NHERF2 protein-dependent process.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Calmodulin kinase II constitut ...... RF2 protein-dependent process.
@ast
Calmodulin kinase II constitut ...... RF2 protein-dependent process.
@en
type
label
Calmodulin kinase II constitut ...... RF2 protein-dependent process.
@ast
Calmodulin kinase II constitut ...... RF2 protein-dependent process.
@en
prefLabel
Calmodulin kinase II constitut ...... RF2 protein-dependent process.
@ast
Calmodulin kinase II constitut ...... RF2 protein-dependent process.
@en
P2093
P2860
P356
P1476
Calmodulin kinase II constitut ...... ERF2 protein-dependent process
@en
P2093
Boyoung Cha
C Ming Tse
Dorotea Bartonicek
Jelena Korac
Mark Donowitz
Mirza Zizak
Nicholas C Zachos
Olga Kovbasnjuk
Rafiquel Sarker
Robert Cole
P2860
P304
13442-13456
P356
10.1074/JBC.M111.307256
P407
P50
P577
2012-02-27T00:00:00Z