Correlation of molecular and functional effects of mutations in cardiac troponin T linked to familial hypertrophic cardiomyopathy: an integrative in silico/in vitro approach
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Animal and in silico models for the study of sarcomeric cardiomyopathiesClinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac Tropomyosin Overlap.A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function.Effects of R92 mutations in mouse cardiac troponin T are influenced by changes in myosin heavy chain isoform.Significance of troponin dynamics for Ca2+-mediated regulation of contraction and inherited cardiomyopathy.Molecular effects of familial hypertrophic cardiomyopathy-related mutations in the TNT1 domain of cTnT.Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: a novel pathogenic mechanism for hypertrophic cardiomyopathy.Atomic resolution probe for allostery in the regulatory thin filament.The tropomyosin binding region of cardiac troponin T modulates crossbridge recruitment dynamics in rat cardiac muscle fibers.Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient-Derived iPSC ModelCardiac muscle activation blunted by a mutation to the regulatory component, troponin TInsights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants-Genotype to Cellular Phenotype.Inherited cardiomyopathies caused by troponin mutations.Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility.Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.Genomic Insights into Cardiomyopathies: A Comparative Cross-Species Review.Molecular mechanisms and structural features of cardiomyopathy-causing troponin T mutants in the tropomyosin overlap region.The structural basis of alpha-tropomyosin linked (Asp230Asn) familial dilated cardiomyopathy.Recent Developments in the Genetics of Cardiomyopathies
P2860
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P2860
Correlation of molecular and functional effects of mutations in cardiac troponin T linked to familial hypertrophic cardiomyopathy: an integrative in silico/in vitro approach
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Correlation of molecular and f ...... ve in silico/in vitro approach
@ast
Correlation of molecular and f ...... ve in silico/in vitro approach
@en
type
label
Correlation of molecular and f ...... ve in silico/in vitro approach
@ast
Correlation of molecular and f ...... ve in silico/in vitro approach
@en
prefLabel
Correlation of molecular and f ...... ve in silico/in vitro approach
@ast
Correlation of molecular and f ...... ve in silico/in vitro approach
@en
P2093
P2860
P356
P1476
Correlation of molecular and f ...... ve in silico/in vitro approach
@en
P2093
Edward P Manning
Jil C Tardiff
Pia J Guinto
P2860
P304
14515-14523
P356
10.1074/JBC.M111.257436
P407
P577
2012-02-13T00:00:00Z