RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates.
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Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factorstRNA fragments in human health and diseaseStructure of RNA 3′-phosphate cyclase bound to substrate RNAStructural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OHStructure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair systemStructures of the Noncanonical RNA Ligase RtcB Reveal the Mechanism of Histidine GuanylylationA tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligationRNA circularization strategies in vivo and in vitroCARF and WYL domains: ligand-binding regulators of prokaryotic defense systemsHSPC117 is regulated by epigenetic modification and is involved in the migration of JEG-3 cellsImpact of DNA3'pp5'G capping on repair reactions at DNA 3' ends.Structure and mechanism of E. coli RNA 2',3'-cyclic phosphodiesterase.RTCB-1 mediates neuroprotection via XBP-1 mRNA splicing in the unfolded protein response pathway.Effects of DNA3'pp5'G capping on 3' end repair reactions and of an embedded pyrophosphate-linked guanylate on ribonucleotide surveillance.Characterization of a novel eukaryal nick-sealing RNA ligase from Naegleria gruberiDNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition.RNA damage in biological conflicts and the diversity of responding RNA repair systemsCoevolution of RtcB and Archease created a multiple-turnover RNA ligaseCharacterization of 3'-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5'-Phosphate Capping Activity of RtcB3.The sequential 2',3'-cyclic phosphodiesterase and 3'-phosphate/5'-OH ligation steps of the RtcB RNA splicing pathway are GTP-dependentDiscovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses.Cross-over of RNA 3'-phosphate ligase into the DNA worldRewriting the rules for end joining via enzymatic splicing of DNA 3'-PO4 and 5'-OH ends.Effects of 3'-OH and 5'-PO4 base mispairs and damaged base lesions on the fidelity of nick sealing by Deinococcus radiodurans RNA ligaseHandling tRNA introns, archaeal way and eukaryotic way.Distinctive kinetics and substrate specificities of plant and fungal tRNA ligasesThe essential function of the Trypanosoma brucei Trl1 homolog in procyclic cells is maturation of the intron-containing tRNATyr.Characterization of Runella slithyformis HD-Pnk, a bifunctional DNA/RNA end-healing enzyme composed of an N-terminal 2',3' -phosphoesterase HD domain and a C-terminal 5' -OH polynucleotide kinase domain.The RNA ligase RtcB reverses MazF-induced ribosome heterogeneity in Escherichia coli.Cellular and molecular phenotypes depending upon the RNA repair system RtcAB of Escherichia coli.Cleavage of 3'-terminal adenosine by archaeal ATP-dependent RNA ligase.Distinct Contributions of Enzymic Functional Groups to the 2',3'-Cyclic Phosphodiesterase, 3'-Phosphate Guanylylation, and 3'-ppG/5'-OH Ligation Steps of the Escherichia coli RtcB Nucleic Acid Splicing Pathway.Mechanism of RNA 2',3'-cyclic phosphate end healing by T4 polynucleotide kinase-phosphatase.Characterization of the tRNA ligases of pathogenic fungi Aspergillus fumigatus and Coccidioides immitis.Cap snatching in yeast L-BC double-stranded RNA totivirus.2'-Phosphate cyclase activity of RtcA: a potential rationale for the operon organization of RtcA with an RNA repair ligase RtcB in Escherichia coli and other bacterial taxa.Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase.Genetic bypass of essential RNA repair enzymes in budding yeast.Site-Selective RNA Splicing Nanozyme: DNAzyme and RtcB Conjugates on a Gold Nanoparticle.Homology model of the human tRNA splicing ligase RtcB.
P2860
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P2860
RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
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2012年學術文章
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2012年學術文章
@zh-hant
name
RNA ligase RtcB splices 3'-pho ...... ide-(3')pp(5')G intermediates.
@ast
RNA ligase RtcB splices 3'-pho ...... ide-(3')pp(5')G intermediates.
@en
type
label
RNA ligase RtcB splices 3'-pho ...... ide-(3')pp(5')G intermediates.
@ast
RNA ligase RtcB splices 3'-pho ...... ide-(3')pp(5')G intermediates.
@en
prefLabel
RNA ligase RtcB splices 3'-pho ...... ide-(3')pp(5')G intermediates.
@ast
RNA ligase RtcB splices 3'-pho ...... ide-(3')pp(5')G intermediates.
@en
P2093
P2860
P356
P1476
RNA ligase RtcB splices 3'-pho ...... ide-(3')pp(5')G intermediates.
@en
P2093
Anupam K Chakravarty
Brian T Chait
Roman Subbotin
P2860
P304
P356
10.1073/PNAS.1201207109
P407
P577
2012-04-02T00:00:00Z