Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
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Human MLH1 suppresses the insertion of telomeric sequences at intra-chromosomal sites in telomerase-expressing cells.Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods.The MLH1 ATPase domain is needed for suppressing aberrant formation of interstitial telomeric sequences.
P2860
Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
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Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
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Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
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type
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Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
@ast
Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
@en
prefLabel
Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
@ast
Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
@en
P2093
P2860
P1476
Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome
@en
P2093
P2860
P304
P356
10.1107/S2053230X15010183
P577
2015-07-28T00:00:00Z