Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation
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S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer.mTOR signaling for biological control and cancer.Association between insulin-like growth factor-1 receptor (IGF1R) negativity and poor prognosis in a cohort of women with primary breast cancer.mTOR inhibitors alone and in combination with JAK2 inhibitors effectively inhibit cells of myeloproliferative neoplasms.The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.Down-regulation of programmed cell death 4 (PDCD4) is associated with aromatase inhibitor resistance and a poor prognosis in estrogen receptor-positive breast cancer.The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells.The role of S6K1 in ER-positive breast cancer.Tamoxifen Action in ER-Negative Breast Cancer.ERRα Is a Marker of Tamoxifen Response and Survival in Triple-Negative Breast CancermTORC1 directly phosphorylates and activates ERα upon estrogen stimulation.The mTOR effectors 4EBP1 and S6K2 are frequently coexpressed, and associated with a poor prognosis and endocrine resistance in breast cancer: a retrospective study including patients from the randomised Stockholm tamoxifen trialsHyperphosphorylation of RPS6KB1, rather than overexpression, predicts worse prognosis in non-small cell lung cancer patients.Alternative splicing of S6K1 promotes non-small cell lung cancer survival.Tumour biology of obesity-related cancers: understanding the molecular concept for better diagnosis and treatment.p70S6 kinase mediates breast cancer cell survival in response to surgical wound fluid stimulation.S6K1 inhibition enhances tamoxifen-induced cell death in MCF-7 cells through translational inhibition of Mcl-1 and survivin.Estrogen induces RAD51C expression and localization to sites of DNA damageRaptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer.Inhibition of breast cancer local relapse by targeting p70S6 kinase activity.Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer.S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.Autophagy of macrophages is regulated by PI3k/Akt/mTOR signalling in the development of diabetic encephalopathy
P2860
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P2860
Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
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2012年论文
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2012年论文
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name
Estrogenic regulation of S6K1 ...... east cancer cell proliferation
@ast
Estrogenic regulation of S6K1 ...... east cancer cell proliferation
@en
type
label
Estrogenic regulation of S6K1 ...... east cancer cell proliferation
@ast
Estrogenic regulation of S6K1 ...... east cancer cell proliferation
@en
prefLabel
Estrogenic regulation of S6K1 ...... east cancer cell proliferation
@ast
Estrogenic regulation of S6K1 ...... east cancer cell proliferation
@en
P2093
P2860
P356
P1433
P1476
Estrogenic regulation of S6K1 ...... east cancer cell proliferation
@en
P2093
A S Shachter
D M Maruani
E N Harris
S Herrero-González
T N Spiegel
P2860
P2888
P304
P356
10.1038/ONC.2011.657
P407
P577
2012-01-30T00:00:00Z
P5875
P6179
1034923211