Demonstration of a longitudinal concentration gradient along scala tympani by sequential sampling of perilymph from the cochlear apex.
about
Intracochlear Drug Injections through the Round Window Membrane: Measures to Improve Drug Retention.In vitro and in vivo pharmacokinetic study of a dexamethasone-releasing silicone for cochlear implants.Differential effects of AAV.BDNF and AAV.Ntf3 in the deafened adult guinea pig ear.Influence of cochleostomy and cochlear implant insertion on drug gradients following intratympanic application in Guinea pigsDistribution of dexamethasone and preservation of inner ear function following intratympanic delivery of a gel-based formulation.Nutrient plasma levels achieved during treatment that reduces noise-induced hearing loss.Biomaterials in cochlear implants.Principles of local drug delivery to the inner ear.Dependence of hearing changes on the dose of intratympanically applied gentamicin: a meta-analysis using mathematical simulations of clinical drug delivery protocols.Effect of cochlear implant electrode insertion on middle-ear function as measured by intra-operative laser Doppler vibrometry.Perilymph Kinetics of FITC-Dextran Reveals Homeostasis Dominated by the Cochlear Aqueduct and Cerebrospinal Fluid.Non-Ototoxic Local Delivery of Bisphosphonate to the Mammalian Cochlea.Marker entry into vestibular perilymph via the stapes following applications to the round window niche of guinea pigs.Marker retention in the cochlea following injections through the round window membrane.Perilymph pharmacokinetics of markers and dexamethasone applied and sampled at the lateral semi-circular canal.Permeability of the round window membrane is influenced by the composition of applied drug solutions and by common surgical proceduresIssues, indications, and controversies regarding intratympanic steroid perfusionConcentration gradient along the scala tympani after local application of gentamicin to the round window membraneEntry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans.Gentamicin concentration gradients in scala tympani perilymph following systemic applications.Developments in delivery of medications for inner ear disease.Perilymph pharmacokinetics of marker applied through a cochlear implant in guinea pigs.Cochlear implants and drug delivery: In vitro evaluation of dexamethasone release.Dexamethasone concentration gradients along scala tympani after application to the round window membrane.Dexamethasone levels and base-to-apex concentration gradients in the scala tympani perilymph after intracochlear delivery in the guinea pig.Cochlear pharmacokinetics with local inner ear drug delivery using a three-dimensional finite-element computer model.Simulation of application strategies for local drug delivery to the inner ear.Cochlear pharmacokinetics of cisplatin: an in vivo study in the guinea pig.Postauricular hypodermic injection to treat inner ear disorders: experimental feasibility study using magnetic resonance imaging and pharmacokinetic comparison.Noninvasive technique for monitoring drug transport through the murine cochlea using micro-computed tomography.Dexamethasone eluting electrodes for cochlear implantation: Effect on residual hearing.[Intratympanic steroid administration: use in the treatment of profound idiopathic sudden sensorineural hearing loss].Intratympanic treatment of intractable unilateral Meniere disease: gentamicin or dexamethasone? A randomized controlled trial.
P2860
Q30315537-5C08BB21-4689-480B-ADA7-ED029E92BE1BQ30316230-8D4CC6C2-C8D0-49C7-8D67-9C5E8C9E8B42Q30398374-48B4E622-2C64-4A56-9B1C-7CAD7D86F8F7Q30431310-AD37ABA5-19BC-4E1E-92D9-D382AF33917EQ30466045-ED179E14-09CE-4147-9B2C-A4B3427B8945Q30466285-DDA57947-A775-410F-92F9-C8E3A536E223Q30472996-309E2C0B-E051-46B2-B426-440E61634FD6Q30478838-C29A3AEA-6331-4DDD-9F10-7168113CC892Q30486355-98256AF4-C32A-4523-AF99-794EFE60F774Q33399299-8CD5D8A9-2B8F-4F64-AF15-68741E4994EBQ35561882-5DC64574-0930-49A5-BE70-5A428CC841CAQ35748623-4863C16A-4080-4CCE-910A-04F825AC22E1Q35751379-116DF1E3-DE8C-4A2C-8060-E2C1A23B9D64Q36088865-34087B5C-D79E-466B-BA4B-2CE878138653Q36421098-74C99F2C-1028-434C-987D-973A6A0AAB19Q37000346-3660470C-9A43-4C04-A551-EE7B0C011015Q37146991-7BBD8DBA-1520-47E0-857B-275C1F333754Q37309543-6E9005D5-BB68-4C24-AB25-F85EB775CF26Q37311062-BE7F3AC1-874C-4773-86F0-05AA69A2C969Q37570016-C9043DA4-22B3-4750-AA59-D38EF1F6E57DQ38096427-5EF1A821-419C-46C7-A905-41E2AC57FE8CQ38619862-EC71C3D6-012D-48CF-8AB6-7871A84CC3C4Q39357184-9F80D3C8-9DFA-4AD0-A085-CAB2DD9CB2E3Q41641420-540E61B5-C402-41AE-AB48-32E408B7D306Q41810387-712E5B80-0999-4F3E-BC7D-E30940F8BC13Q41931676-99A0B2B0-F7A7-423B-90D2-AA9161C70E2AQ41938982-548D18D4-9881-4DF6-8AC4-149CA5FC8F49Q42439712-91AE215B-222C-47D5-8246-325CCFB7C624Q45766504-37CC250A-5C86-49BA-AE4F-67EA4F8E4487Q46053474-D541B65E-4015-4467-B8A9-129D7BB19223Q50425940-866B9DD7-C2E5-4F90-B7C5-334D6E8897A6Q50430053-2B559360-6ADD-4923-949D-C89338109728Q50432428-0196AA72-0154-4165-AF5A-44BDA09838F1
P2860
Demonstration of a longitudinal concentration gradient along scala tympani by sequential sampling of perilymph from the cochlear apex.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Demonstration of a longitudina ...... ilymph from the cochlear apex.
@ast
Demonstration of a longitudina ...... ilymph from the cochlear apex.
@en
type
label
Demonstration of a longitudina ...... ilymph from the cochlear apex.
@ast
Demonstration of a longitudina ...... ilymph from the cochlear apex.
@en
prefLabel
Demonstration of a longitudina ...... ilymph from the cochlear apex.
@ast
Demonstration of a longitudina ...... ilymph from the cochlear apex.
@en
P2093
P2860
P1433
P1476
Demonstration of a longitudina ...... rilymph from the cochlear apex
@en
P2093
Robert Mynatt
Ruth M Gill
Shane A Hale
Stefan K Plontke
P2860
P2888
P304
P356
10.1007/S10162-006-0034-Y
P50
P577
2006-04-22T00:00:00Z