Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.
about
Targeting the latent reservoir to achieve functional HIV curePost-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virusBone Marrow Gene Therapy for HIV/AIDSPre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized miceNew generation humanized mice for virus research: comparative aspects and future prospectsGene therapy strategies for HIV/AIDS: preclinical modeling in humanized miceCD25 preselective anti-HIV vectors for improved HIV gene therapy.Optimized lentiviral vectors for HIV gene therapy: multiplexed expression of small RNAs and inclusion of MGMT(P140K) drug resistance geneR88-APOBEC3Gm Inhibits the Replication of Both Drug-resistant Strains of HIV-1 and Viruses Produced From Latently Infected CellsCombinatorial anti-HIV gene therapy: using a multipronged approach to reach beyond HAARTA quantitative comparison of anti-HIV gene therapy delivered to hematopoietic stem cells versus CD4+ T cells.Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice.BLT humanized mice as a small animal model of HIV infection.Hallmarks of HIV-1 pathogenesis are modulated by Nef's Secretion Modification RegionA cross-species view on virusesMultilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDSHost Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic ApproachesPreclinical in vivo evaluation of the safety of a multi-shRNA-based gene therapy against HIV-1Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1.Genetic modification of hematopoietic stem cells as a therapy for HIV/AIDS.Creating genetic resistance to HIV.Using TRIM5α as an HIV therapeutic: the alpha gene?Stem cell transplantation in the context of HIV--how can we cure HIV infection?Practical considerations in gene therapy for HIV cure.HIV/AIDS: modified stem cells in the spotlight.Targeting HIV latency: resting memory T cells, hematopoietic progenitor cells and future directions.Stem cell gene therapy for HIV: strategies to inhibit viral entry and replication.Cell therapies for treatment of human immunodeficiency virus infection.Recent advances in RNAi-based strategies for therapy and prevention of HIV-1/AIDS.Stem cell-based therapies for HIV/AIDS.Gene transfer of two entry inhibitors protects CD4⁺ T cell from HIV-1 infection in humanized mice.The therapeutic landscape of HIV-1 via genome editingGeneration of an HIV resistant T-cell line by targeted "stacking" of restriction factors.RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice.Combinatorial CRISPR-Cas9 and RNA Interference Attack on HIV-1 DNA and RNA Can Lead to Cross-Resistance.Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells.A novel approach to block HIV-1 coreceptor CXCR4 in non-toxic manner.False-positive HIV PCR test following ex vivo lentiviral gene transfer treatment of X-linked severe combined immunodeficiency vector.Targeting TRIM5α in HIV Cure Strategies for the CRISPR-Cas9 Era.Cell and Gene Therapy for HIV Cure.
P2860
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P2860
Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Generation of an HIV-1-resista ...... on anti-HIV lentiviral vector.
@ast
Generation of an HIV-1-resista ...... on anti-HIV lentiviral vector.
@en
type
label
Generation of an HIV-1-resista ...... on anti-HIV lentiviral vector.
@ast
Generation of an HIV-1-resista ...... on anti-HIV lentiviral vector.
@en
prefLabel
Generation of an HIV-1-resista ...... on anti-HIV lentiviral vector.
@ast
Generation of an HIV-1-resista ...... on anti-HIV lentiviral vector.
@en
P2093
P2860
P356
P1433
P1476
Generation of an HIV-1-resista ...... ion anti-HIV lentiviral vector
@en
P2093
Catherine Nacey
Gerhard Bauer
Jeannine McGee
Jon E Walker
Joseph S Anderson
Mehrdad Abedi
Rachel X Chen
Richard B Pollard
P2860
P304
P356
10.1128/JVI.06300-11
P407
P50
P577
2012-03-07T00:00:00Z