In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity
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Emergence of micronuclei as a genomic biomarkerEmerging metrology for high-throughput nanomaterial genotoxicologyGenotoxicity of TiO2 nanoparticles assessed by mini-gel comet assay and micronucleus scoring with flow cytometryPre-exposure to 50 Hz magnetic fields modifies menadione-induced genotoxic effects in human SH-SY5Y neuroblastoma cellsHigh throughput toxicity screening and intracellular detection of nanomaterialsOptimized automated data analysis for the cytokinesis-block micronucleus assay using imaging flow cytometry for high throughput radiation biodosimetry.High content flow cytometric micronucleus scoring method is applicable to attachment cell linesEvaluation of the automated MicroFlow® and Metafer™ platforms for high-throughput micronucleus scoring and dose response analysis in human lymphoblastoid TK6 cells.Genetic stability of bone marrow-derived human mesenchymal stromal cells in the Quantum SystemDioxin induces genomic instability in mouse embryonic fibroblasts.Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose-response relationships.Automated analysis of the cytokinesis-block micronucleus assay for radiation biodosimetry using imaging flow cytometry.Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension.Factors affecting the in vitro micronucleus assay for evaluation of nanomaterials.Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure.Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assayThe in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance.High-content analysis/screening for predictive toxicology: application to hepatotoxicity and genotoxicity.Induction of micronuclei and superoxide production in neuroblastoma and glioma cell lines exposed to weak 50 Hz magnetic fields.Flow cytometry vs optical microscopy in the evaluation of the genotoxic potential of xenobiotic compounds.Cellular detection of 50 Hz magnetic fields and weak blue light: effects on superoxide levels and genotoxicity.Co-assessment of cell cycle and micronucleus frequencies demonstrates the influence of serum on the in vitro genotoxic response to amorphous monodisperse silica nanoparticles of varying sizes.Nitroxide TEMPO: a genotoxic and oxidative stress inducer in cultured cells.Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: protocol optimization and transferability assessment.Resveratrol acts as a topoisomerase II poison in human glioma cells.In vitro micronucleus screening of pharmaceutical candidates by flow cytometry in Chinese hamster V79 cells.A flow cytometry based in vitro micronucleus assay in TK6 cells--validation using early stage pharmaceutical development compounds.DEK over-expression promotes mitotic defects and micronucleus formation.Adapting the buccal micronucleus cytome assay for use in wild birds: age and sex affect background frequency in pigeons.An evaluation of 25 selected ToxCast chemicals in medium-throughput assays to detect genotoxicity.Genetic and rat toxicity studies of cyclodextrin glucanotransferase.Cold Atmospheric Plasma Induces Apoptosis and Oxidative Stress Pathway Regulation in T-Lymphoblastoid Leukemia Cells.Cytotoxicity and genotoxicity of nano - and microparticulate copper oxide: role of solubility and intracellular bioavailability.Nonlinear responses for chromosome and gene level effects induced by vinyl acetate monomer and its metabolite, acetaldehyde in TK6 cells.Long-term storage does not alter functionality of in vitro generated human erythroblasts: implications for ex vivo generated erythroid transfusion products.Miniaturized flow cytometry-based CHO-K1 micronucleus assay discriminates aneugenic and clastogenic modes of action.In vivo micronucleus screening in zebrafish by flow cytometry.Bioengineering a non-genotoxic vector for genetic modification of mesenchymal stem cells.Adduction to arginine detoxifies aflatoxin B1 by eliminating genotoxicity and altering in vitro toxicokinetic profiles.Multi-parameter dose estimations in radiation biodosimetry using the automated cytokinesis-block micronucleus assay with imaging flow cytometry.
P2860
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P2860
In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
In vitro micronucleus assay sc ...... enetic damage and cytotoxicity
@ast
In vitro micronucleus assay sc ...... enetic damage and cytotoxicity
@en
type
label
In vitro micronucleus assay sc ...... enetic damage and cytotoxicity
@ast
In vitro micronucleus assay sc ...... enetic damage and cytotoxicity
@en
prefLabel
In vitro micronucleus assay sc ...... enetic damage and cytotoxicity
@ast
In vitro micronucleus assay sc ...... enetic damage and cytotoxicity
@en
P2093
P2860
P1433
P1476
In vitro micronucleus assay sc ...... enetic damage and cytotoxicity
@en
P2093
Jeffrey C Bemis
Stephen D Dertinger
Steven M Bryce
Svetlana L Avlasevich
P2860
P356
10.1016/J.MRGENTOX.2007.03.002
P407
P577
2007-03-19T00:00:00Z