Substrate-dependent millisecond domain motions in DNA polymerase β.
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The E295K Cancer Variant of Human Polymerase Favors the Mismatch Conformational Pathway during Nucleotide SelectionUltrafast water dynamics at the interface of the polymerase-DNA binding complexSubstrate-induced DNA polymerase β activation."Gate-keeper" residues and active-site rearrangements in DNA polymerase μ help discriminate non-cognate nucleotides.Mapping the structural and dynamical features of multiple p53 DNA binding domains: insights into loop 1 intrinsic dynamics.Real-time surface plasmon resonance study of biomolecular interactions between polymerase and bulky mutagenic DNA lesions.Using NMR spectroscopy to elucidate the role of molecular motions in enzyme functionNMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers.Direct correlation of DNA binding and single protein domain motion via dual illumination fluorescence microscopy.Role of Conformational Motions in Enzyme Function: Selected Methodologies and Case Studies.I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity
P2860
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P2860
Substrate-dependent millisecond domain motions in DNA polymerase β.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Substrate-dependent millisecond domain motions in DNA polymerase β.
@ast
Substrate-dependent millisecond domain motions in DNA polymerase β.
@en
type
label
Substrate-dependent millisecond domain motions in DNA polymerase β.
@ast
Substrate-dependent millisecond domain motions in DNA polymerase β.
@en
prefLabel
Substrate-dependent millisecond domain motions in DNA polymerase β.
@ast
Substrate-dependent millisecond domain motions in DNA polymerase β.
@en
P2093
P2860
P1476
Substrate-dependent millisecond domain motions in DNA polymerase β
@en
P2093
J Patrick Loria
Joann B Sweasy
Monalisa Swain
Shibani Dalal
P2860
P304
P356
10.1016/J.JMB.2012.03.013
P407
P577
2012-03-23T00:00:00Z