Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies

Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies

Item
http://www.wikidata.org/entity/Q35949372
Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia.Targeting the CXCL12/CXCR4 axis in acute myeloid leukemia: from bench to bedside.A phase 1/2 study of chemosensitization with plerixafor plus G-CSF in relapsed or refractory acute myeloid leukemia.Drug design strategies focusing on the CXCR4/CXCR7/CXCL12 pathway in leukemia and lymphoma.Mesenchymal Stem Cells in Myeloid Malignancies: A Focus on Immune Escaping and Therapeutic Implications.The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.Distinct mobilization of leukocytes and hematopoietic stem cells by CXCR4 peptide antagonist LY2510924 and monoclonal antibody LY2624587.Waldenstrom's Macroglobulinemia: An Update.Monoclonal Antibody Therapies for Hematological Malignancies: Not Just Lineage-Specific Targets.Regulation of Malignant Hematopoiesis by Bone Marrow Microenvironment.Phase I dose-escalation study of F50067, a humanized anti-CXCR4 monoclonal antibody alone and in combination with lenalidomide and low-dose dexamethasone, in relapsed or refractory multiple myeloma.A mouse model for evaluation of efficacy and concomitant toxicity of anti-human CXCR4 therapeutics.CXCR4-directed theranostics in oncology and inflammationPotential use of compounds from sea cucumbers as MDM2 and CXCR4 inhibitors to control cancer cell growth
P2860

Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies

Item
http://www.wikidata.org/entity/Q35949372
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Inhibition of CXCR4 by LY26245 ...... is of Hematologic Malignancies
@ast
Inhibition of CXCR4 by LY26245 ...... is of Hematologic Malignancies
@en
type
label
Inhibition of CXCR4 by LY26245 ...... is of Hematologic Malignancies
@ast
Inhibition of CXCR4 by LY26245 ...... is of Hematologic Malignancies
@en
prefLabel
Inhibition of CXCR4 by LY26245 ...... is of Hematologic Malignancies
@ast
Inhibition of CXCR4 by LY26245 ...... is of Hematologic Malignancies
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
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P1433
P1476
Inhibition of CXCR4 by LY26245 ...... is of Hematologic Malignancies
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0150585
P407
P433
P478
P577
P5875
P698
P932