The silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressor is required for full estrogen receptor alpha transcriptional activity.
about
DNA homologous recombination factor SFR1 physically and functionally interacts with estrogen receptor alphaActivation of p53 transcriptional activity by SMRT: a histone deacetylase 3-independent function of a transcriptional corepressorCoactivators and corepressors: what's in a name?Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration networkRole of chaperone mediated autophagy (CMA) in the degradation of misfolded N-CoR protein in non-small cell lung cancer (NSCLC) cellsEstrogen-regulated prohibitin is required for mouse uterine development and adult function.Characterization of the oestrogenic activity of non-aromatic steroids: are there male-specific endogenous oestrogen receptor modulators?Estrogen receptors recruit SMRT and N-CoR corepressors through newly recognized contacts between the corepressor N terminus and the receptor DNA binding domain.Global characterization of transcriptional impact of the SRC-3 coregulatorCooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor.The SMRT coregulator enhances growth of estrogen receptor-α-positive breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis.Nuclear receptor corepressor complexes in cancer: mechanism, function and regulationDistinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.What goes on behind closed doors: physiological versus pharmacological steroid hormone actions.Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics.Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapyGenome-scale techniques highlight the epigenome and redefine fundamental principles of gene regulation.Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.Regulated clearance of histone deacetylase 3 protects independent formation of nuclear receptor corepressor complexes.miRNAs and estrogen action.Differential copy number aberrations in novel candidate genes associated with progression from in situ to invasive ductal carcinoma of the breast.Epigenetic Therapy in Breast Cancer.Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrenceRaloxifene inhibits growth of RT4 urothelial carcinoma cells via estrogen receptor-dependent induction of apoptosis and inhibition of proliferation.Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genesEpigenetic targeting in breast cancer: therapeutic impact and future direction.The role of retinoblastoma-associated proteins 46 and 48 in estrogen receptor alpha mediated gene expressionInteraction of glucocorticoid receptor (GR) with estrogen receptor (ER) α and activator protein 1 (AP1) in dexamethasone-mediated interference of ERα activityUnique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.p150/glued modifies nuclear estrogen receptor functionEstrogen Regulation of MicroRNA ExpressionWho's in charge? Nuclear receptor coactivator and corepressor function in brain and behavior.Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells.G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation.An evolving understanding of nuclear receptor coregulator proteins.Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimersThe homeodomain protein HOXB13 regulates the cellular response to androgens.Estradiol downregulation of the tumor suppressor gene BTG2 requires estrogen receptor-alpha and the REA corepressor.Activin regulates estrogen receptor gene expression in the mouse ovary.
P2860
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P2860
The silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressor is required for full estrogen receptor alpha transcriptional activity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The silencing mediator of reti ...... lpha transcriptional activity.
@ast
The silencing mediator of reti ...... lpha transcriptional activity.
@en
type
label
The silencing mediator of reti ...... lpha transcriptional activity.
@ast
The silencing mediator of reti ...... lpha transcriptional activity.
@en
prefLabel
The silencing mediator of reti ...... lpha transcriptional activity.
@ast
The silencing mediator of reti ...... lpha transcriptional activity.
@en
P2093
P2860
P356
P1476
The silencing mediator of reti ...... lpha transcriptional activity.
@en
P2093
Carolyn L Smith
Margaret C Pace
Sudipan Karmakar
Theresa J Peterson
P2860
P304
P356
10.1128/MCB.00237-07
P407
P577
2007-06-25T00:00:00Z